OBJECTIVE: Obsessive compulsive disorder (OCD) is a clinically heterogeneous disorder; OCD with poor insight has been suggested to be a specific clinical subtype. Neurological soft signs (NSSs) may be helpful to identify the specific subtypes of OCD patients. METHODS: In the present study, we aimed to compare OCD patients with poor insight with OCD patients having good insight, and healthy individuals. Sixty-four OCD patients (38 with good insight and 26 with poor insight), and 32 healthy subjects were enrolled in the present study. The Overvalued Ideas Scale (OVIS) was used to determine OCD patients with poor insight. NSSs were assessed by using the Neurological Evaluation Scale (NES). RESULTS: Two OCD groups had significantly higher total NES scores compared to controls (p=.000). Compared to healthy controls, OCD patients with poor insight performed significantly worse on all NES subscales, and they had significantly more NSSs on motor coordination, and sensory integration subscales compared to the OCD with good insight group. CONCLUSION: Our results suggested that OCD patients with poor insight exhibit more extensive neurodevelopmental impairments compared to OCD patients with good insight.
OBJECTIVE:Obsessive compulsive disorder (OCD) is a clinically heterogeneous disorder; OCD with poor insight has been suggested to be a specific clinical subtype. Neurological soft signs (NSSs) may be helpful to identify the specific subtypes of OCDpatients. METHODS: In the present study, we aimed to compare OCDpatients with poor insight with OCDpatients having good insight, and healthy individuals. Sixty-four OCDpatients (38 with good insight and 26 with poor insight), and 32 healthy subjects were enrolled in the present study. The Overvalued Ideas Scale (OVIS) was used to determine OCDpatients with poor insight. NSSs were assessed by using the Neurological Evaluation Scale (NES). RESULTS: Two OCD groups had significantly higher total NES scores compared to controls (p=.000). Compared to healthy controls, OCDpatients with poor insight performed significantly worse on all NES subscales, and they had significantly more NSSs on motor coordination, and sensory integration subscales compared to the OCD with good insight group. CONCLUSION: Our results suggested that OCDpatients with poor insight exhibit more extensive neurodevelopmental impairments compared to OCDpatients with good insight.
Authors: Wanting Liu; Jun Gan; Jie Fan; Hong Zheng; Sihui Li; Raymond C K Chan; Changlian Tan; Xiongzhao Zhu Journal: Neuroimage Clin Date: 2019-10-16 Impact factor: 4.881
Authors: Igor Elman; Tamara V Gurvits; Evelyne Tschibelu; Justin D Spring; Natasha B Lasko; Roger K Pitman Journal: PLoS One Date: 2013-04-04 Impact factor: 3.240
Authors: Rajshekhar Bipeta; Srinivasa Srr Yerramilli; Srilakshmi Pingali; Ashok Reddy Karredla; Mohammad Osman Ali Journal: Child Adolesc Psychiatry Ment Health Date: 2013-06-20 Impact factor: 3.033