Literature DB >> 21396215

High prevalence of asthma and atopy in the Canary Islands, Spain.

G Juliá-Serdá1, P Cabrera-Navarro, O Acosta-Fernández, P Martín-Pérez, P Losada-Cabrera, M A García-Bello, T Carrillo-Díaz, J Antó-Boqué.   

Abstract

OBJECTIVE: To evaluate the prevalence of and risk factors for asthma and related conditions in the Canaries, Spain.
METHODS: From a randomised sample of 9506 adults aged 20-44 years who answered a short questionnaire, a random sample corresponding to 20% of the original was taken. Subjects classified as symptomatic in the previous survey and who were not included in the random sample were also invited to participate. The subjects completed a respiratory questionnaire, and underwent spirometry, bronchial hyperresponsiveness (BHR) test, skin tests and immunoglobulin E (IgE) measurements.
RESULTS: The random sample included 593 subjects. The prevalence of skin sensitisation to mites was 30.3% (95%CI 26.7-34.2) and the prevalence of IgE to mites 30.5% (95%CI 26.2-35.2). A prevalence of 40.6% (95%CI 35.9-45.5) was found for atopy, 14.1% (95%CI 11.1-17.1) for BHR and 4.2% (95%CI, 2.5-5.9) for asthma. The risk factors most strongly associated with asthma were atopy (OR 4.89, 95%CI 3.07-7.78) and respiratory infection before the age of 5 years (OR 2.78, 95%CI 1.66-4.67).
CONCLUSION: This study shows a high prevalence of sensitisation to mites, atopy, BHR and asthma in the Canaries, similar to that observed in English-speaking countries. We suggest that these findings could partially result from climatic conditions.

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Year:  2011        PMID: 21396215     DOI: 10.5588/ijtld.10.0303

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN: 1027-3719            Impact factor:   2.373


  7 in total

1.  No association between genetic ancestry and susceptibility to asthma or atopy in Canary Islanders.

Authors:  María Pino-Yanes; Almudena Corrales; José Cumplido; Ruperto González; María José Torres-Galván; Orlando Acosta Fernández; Inmaculada Sánchez-Machín; Javier Figueroa; Anselmo Sánchez-Palacios; Jesús Villar; Mariano Hernández; Teresa Carrillo; Carlos Flores
Journal:  Immunogenetics       Date:  2012-06-19       Impact factor: 2.846

2.  The Canary Islands as a model of risk of pulmonary dirofilariasis in a hyperendemic area.

Authors:  Elena D Cabrera; Elena Carretón; Rodrigo Morchón; Yaiza Falcón-Cordón; Soraya Falcón-Cordón; Fernando Simón; J Alberto Montoya-Alonso
Journal:  Parasitol Res       Date:  2018-02-02       Impact factor: 2.289

Review 3.  Operational definitions of asthma in recent epidemiological studies are inconsistent.

Authors:  Ana Sá-Sousa; Tiago Jacinto; Luís Filipe Azevedo; Mário Morais-Almeida; Carlos Robalo-Cordeiro; António Bugalho-Almeida; Jean Bousquet; João Almeida Fonseca
Journal:  Clin Transl Allergy       Date:  2014-08-04       Impact factor: 5.871

4.  Targeted analysis of genomic regions enriched in African ancestry reveals novel classical HLA alleles associated with asthma in Southwestern Europeans.

Authors:  Eva Suarez-Pajes; Claudio Díaz-García; Héctor Rodríguez-Pérez; Jose M Lorenzo-Salazar; Itahisa Marcelino-Rodríguez; Almudena Corrales; Xiuwen Zheng; Ariel Callero; Eva Perez-Rodriguez; Jose C Garcia-Robaina; Rafaela González-Montelongo; Carlos Flores; Beatriz Guillen-Guio
Journal:  Sci Rep       Date:  2021-12-08       Impact factor: 4.379

5.  Contribution of allergy in the acquisition of uncontrolled severe asthma.

Authors:  María Isabel Delgado Dolset; David Obeso; Juan Rodriguez-Coira; Alma Villaseñor; Heleia González Cuervo; Ana Arjona; Coral Barbas; Domingo Barber; Teresa Carrillo; María M Escribese
Journal:  Front Med (Lausanne)       Date:  2022-09-21

6.  Genomic Analyses of Human European Diversity at the Southwestern Edge: Isolation, African Influence and Disease Associations in the Canary Islands.

Authors:  Beatriz Guillen-Guio; Jose M Lorenzo-Salazar; Rafaela González-Montelongo; Ana Díaz-de Usera; Itahisa Marcelino-Rodríguez; Almudena Corrales; Antonio Cabrera de León; Santos Alonso; Carlos Flores
Journal:  Mol Biol Evol       Date:  2018-12-01       Impact factor: 16.240

7.  The Genomics and Metagenomics of Asthma Severity (GEMAS) Study: Rationale and Design.

Authors:  Javier Perez-Garcia; José M Hernández-Pérez; Ruperto González-Pérez; Olaia Sardón; Elena Martin-Gonzalez; Antonio Espuela-Ortiz; Elena Mederos-Luis; Ariel Callero; Esther Herrera-Luis; Paula Corcuera; Inmaculada Sánchez-Machín; Paloma Poza-Guedes; Luis Manuel González García; Purificación Ramírez-Martín; Lorenzo Pérez-Negrín; Hemily Izaguirre-Flores; Javier Barrios-Recio; Eva Pérez-Rodríguez; Julia Alcoba-Florez; José A Cañas; José M Rodrigo Muñoz; Victoria Del Pozo; Javier Korta-Murua; Lina I Pérez Méndez; Mariano Hernandez-Ferrer; Jesús Villar; Fabian Lorenzo-Diaz; Maria Pino-Yanes
Journal:  J Pers Med       Date:  2020-09-11
  7 in total

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