Literature DB >> 21395371

Integrin antagonists for transplant immunosuppression: panacea or peril?

William H Kitchens, Christian P Larsen, Mandy L Ford.   

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Year:  2011        PMID: 21395371      PMCID: PMC4642442          DOI: 10.2217/imt.10.113

Source DB:  PubMed          Journal:  Immunotherapy        ISSN: 1750-743X            Impact factor:   4.196


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  20 in total

1.  CTLA4Ig combined with anti-LFA-1 prolongs cardiac allograft survival indefinitely.

Authors:  Matthias Corbascio; Helene Ekstrand; Cecilia Osterholm; Zhongquan Qi; Mecislovas Simanaitis; Christian P Larsen; Thomas C Pearson; Kristian Riesbeck; Henrik Ekberg
Journal:  Transpl Immunol       Date:  2002-06       Impact factor: 1.708

Review 2.  Integrins as therapeutic targets: lessons and opportunities.

Authors:  Dermot Cox; Marian Brennan; Niamh Moran
Journal:  Nat Rev Drug Discov       Date:  2010-10       Impact factor: 84.694

3.  LFA-1-specific therapy prolongs allograft survival in rhesus macaques.

Authors:  Idelberto R Badell; Maria C Russell; Peter W Thompson; Alexandra P Turner; Tim A Weaver; Jennifer M Robertson; Jose G Avila; Jose A Cano; Brandi E Johnson; Mingqing Song; Frank V Leopardi; Sarah Swygert; Elizabeth A Strobert; Mandy L Ford; Allan D Kirk; Christian P Larsen
Journal:  J Clin Invest       Date:  2010-11-22       Impact factor: 14.808

4.  A randomized multicenter trial comparing leukocyte function-associated antigen-1 monoclonal antibody with rabbit antithymocyte globulin as induction treatment in first kidney transplantations.

Authors:  M Hourmant; J Bedrossian; D Durand; Y Lebranchu; E Renoult; P Caudrelier; R Buffet; J P Soulillou
Journal:  Transplantation       Date:  1996-12-15       Impact factor: 4.939

5.  Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab.

Authors:  A M Posselt; M D Bellin; M Tavakol; G L Szot; L A Frassetto; U Masharani; R K Kerlan; L Fong; F G Vincenti; B J Hering; J A Bluestone; P G Stock
Journal:  Am J Transplant       Date:  2010-08       Impact factor: 8.086

6.  Experience with a novel efalizumab-based immunosuppressive regimen to facilitate single donor islet cell transplantation.

Authors:  N A Turgeon; J G Avila; J A Cano; J J Hutchinson; I R Badell; A J Page; A B Adams; M H Sears; P H Bowen; A D Kirk; T C Pearson; C P Larsen
Journal:  Am J Transplant       Date:  2010-09       Impact factor: 8.086

7.  A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).

Authors:  F Vincenti; B Charpentier; Y Vanrenterghem; L Rostaing; B Bresnahan; P Darji; P Massari; G A Mondragon-Ramirez; M Agarwal; G Di Russo; C-S Lin; P Garg; C P Larsen
Journal:  Am J Transplant       Date:  2010-03       Impact factor: 8.086

8.  Prolongation of islet allograft survival with an antibody to vascular cell adhesion molecule 1.

Authors:  M D Stegall; A Ostrowska; J Haynes; F Karrer; I Kam; R G Gill
Journal:  Surgery       Date:  1995-08       Impact factor: 3.982

9.  Blockade of very late antigen-4 integrin binding to fibronectin with connecting segment-1 peptide reduces accelerated coronary arteriopathy in rabbit cardiac allografts.

Authors:  S Molossi; M Elices; T Arrhenius; R Diaz; C Coulber; M Rabinovitch
Journal:  J Clin Invest       Date:  1995-06       Impact factor: 14.808

10.  Short-term administrations of a combination of anti-LFA-1 and anti-CD154 monoclonal antibodies induce tolerance to neonatal porcine islet xenografts in mice.

Authors:  Hossein Arefanian; Eric B Tredget; Ray V Rajotte; Ron G Gill; Gregory S Korbutt; Gina R Rayat
Journal:  Diabetes       Date:  2010-01-19       Impact factor: 9.461

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  10 in total

1.  Combined costimulatory and leukocyte functional antigen-1 blockade prevents transplant rejection mediated by heterologous immune memory alloresponses.

Authors:  William H Kitchens; Divya Haridas; Maylene E Wagener; Mingqing Song; Mandy L Ford
Journal:  Transplantation       Date:  2012-05-27       Impact factor: 4.939

Review 2.  The impact of infection and tissue damage in solid-organ transplantation.

Authors:  Anita S Chong; Maria-Luisa Alegre
Journal:  Nat Rev Immunol       Date:  2012-05-25       Impact factor: 53.106

3.  Selective CD28 blockade attenuates CTLA-4-dependent CD8+ memory T cell effector function and prolongs graft survival.

Authors:  Danya Liu; I Raul Badell; Mandy L Ford
Journal:  JCI Insight       Date:  2018-01-11

Review 4.  Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy.

Authors:  Leslie S Kean; Laurence A Turka; Bruce R Blazar
Journal:  Immunol Rev       Date:  2017-03       Impact factor: 12.988

Review 5.  Activation and regulation of alloreactive T cell immunity in solid organ transplantation.

Authors:  Charlotte Duneton; Pamela D Winterberg; Mandy L Ford
Journal:  Nat Rev Nephrol       Date:  2022-07-27       Impact factor: 42.439

Review 6.  Memory T Cells in Transplantation: Old Challenges Define New Directions.

Authors:  Michael Nicosia; Robert L Fairchild; Anna Valujskikh
Journal:  Transplantation       Date:  2020-10       Impact factor: 5.385

Review 7.  Role of Memory T Cells in Allograft Rejection and Tolerance.

Authors:  Gilles Benichou; Bruno Gonzalez; Jose Marino; Katayoun Ayasoufi; Anna Valujskikh
Journal:  Front Immunol       Date:  2017-02-28       Impact factor: 7.561

Review 8.  Costimulation blockade: current perspectives and implications for therapy.

Authors:  Gillian Kinnear; Nick D Jones; Kathryn J Wood
Journal:  Transplantation       Date:  2013-02-27       Impact factor: 4.939

9.  Heterogeneity within T Cell Memory: Implications for Transplant Tolerance.

Authors:  Scott M Krummey; Mandy L Ford
Journal:  Front Immunol       Date:  2012-03-01       Impact factor: 7.561

10.  Transient combination therapy targeting the immune synapse abrogates T cell responses and prolongs allograft survival in mice.

Authors:  Paul M Schroder; Mithun Khattar; Ronghai Deng; Aini Xie; Wenhao Chen; Stanislaw M Stepkowski
Journal:  PLoS One       Date:  2013-07-24       Impact factor: 3.240

  10 in total

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