Literature DB >> 21394476

New S-benzylisothiosemicarbazones with antimycobacterial activity.

E Petrlíková1, K Waisser, L Heinisch, J Stolaříková.   

Abstract

Benzaldehyde- and salicylaldehyde-S-benzylisothiosemicarbazones show a moderate to high in vitro activity against Mycobacterium tuberculosis, Mycobacterium avium and two strains of Mycobacterium kansasii. Benzaldehyde-S-4-bromobenzylisothiosemicarbazone and salicylaldehyde-S-4-chlorobenzylisothiosemicarbazone have the most promising antimycobacterial properties.

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Year:  2011        PMID： 21394476     DOI： 10.1007/s12223-011-0015-3

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.099


  7 in total

1.  [Advances in the development of new antimycobacterial agents. The alkylsulfanyl group--a pharmacophore for antimycobacterial activity].

Authors:  V Klimesová; J Kocí; L Zahajská
Journal:  Ceska Slov Farm       Date:  2002-01

2.  The need for new drugs against tuberculosis. Obstacles, opportunities, and next steps.

Authors:  R J O'Brien; P P Nunn
Journal:  Am J Respir Crit Care Med       Date:  2001-04       Impact factor: 21.405

3.  Global incidence of multidrug-resistant tuberculosis.

Authors:  Matteo Zignol; Mehran S Hosseini; Abigail Wright; Catharina Lambregts-van Weezenbeek; Paul Nunn; Catherine J Watt; Brian G Williams; Christopher Dye
Journal:  J Infect Dis       Date:  2006-07-12       Impact factor: 5.226

4.  [Synthesis and antiviral effect of N-heterocyclic formylisothiosemicarbazones].

Authors:  L Heinisch; M Tonew; E Tonew
Journal:  Pharmazie       Date:  1977-12       Impact factor: 1.267

5.  A comparison of two regimens for the treatment of Mycobacterium avium complex bacteremia in AIDS: rifabutin, ethambutol, and clarithromycin versus rifampin, ethambutol, clofazimine, and ciprofloxacin. Canadian HIV Trials Network Protocol 010 Study Group.

Authors:  S D Shafran; J Singer; D P Zarowny; P Phillips; I Salit; S L Walmsley; I W Fong; M J Gill; A R Rachlis; R G Lalonde; M M Fanning; C M Tsoukas
Journal:  N Engl J Med       Date:  1996-08-08       Impact factor: 91.245

Review 6.  Tuberculosis in HIV-infected patients: a comprehensive review.

Authors:  L Aaron; D Saadoun; I Calatroni; O Launay; N Mémain; V Vincent; G Marchal; B Dupont; O Bouchaud; D Valeyre; O Lortholary
Journal:  Clin Microbiol Infect       Date:  2004-05       Impact factor: 8.067

7.  New antimycobacterial S-alkylisothiosemicarbazones.

Authors:  K Waisser; L Heinisch; M Slosárek; J Janota
Journal:  Folia Microbiol (Praha)       Date:  2005       Impact factor: 2.629
  7 in total

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