Jason Hou1, Hashem El-Serag, Joseph Sellin, Selvi Thirumurthi. 1. Division of Gastroenterology and Hepatology, Baylor College of Medicine Gastroenterology, 1709 Dryden Street Suite 800, Houston, TX 77030, USA. jkhou@bcm.tmc.edu
Abstract
BACKGROUND: Many inflammatory bowel disease (IBD) studies have focused on Caucasian patients and little data exist on IBD in Hispanics living in the United States. AIM: The aim of our study was to compare IBD characteristics between Hispanic and Caucasian patients in the Harris County Hospital District (HCHD). METHODS: We identified patients within the HCHD with a diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) recorded during 2000-2006. Primary medical record review was performed to confirm the diagnosis and to abstract data on patient demographics, disease characteristics and treatment. RESULTS: A total of 69 Hispanic and 83 Caucasian patients with confirmed IBD were analyzed. Hispanics were diagnosed with IBD at an older age than Caucasians (mean age 37.8 SD 16 vs. mean age 29.0 SD 14, P < 0.01). In Hispanics with IBD, there was a lower proportion of patients with CD compared to Caucasians with IBD (36% vs. 65%, P < 0.01). Although there were no significant differences in diagnostic examinations or medication prescription between the two groups, there was a higher number of bowel resections per patient in Caucasians compared with Hispanics (0.5 vs. 0.22, P = 0.01). CONCLUSIONS: Hispanics with IBD were diagnosed at a significantly older age than Caucasians and had a lower number of bowel resections per patient. In Hispanics with IBD, UC was more common than CD while CD was more common than UC among Caucasians with IBD. Further research is required to confirm these observations and determine if these findings reflect genetic or environmental differences.
BACKGROUND: Many inflammatory bowel disease (IBD) studies have focused on Caucasian patients and little data exist on IBD in Hispanics living in the United States. AIM: The aim of our study was to compare IBD characteristics between Hispanic and Caucasian patients in the Harris County Hospital District (HCHD). METHODS: We identified patients within the HCHD with a diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) recorded during 2000-2006. Primary medical record review was performed to confirm the diagnosis and to abstract data on patient demographics, disease characteristics and treatment. RESULTS: A total of 69 Hispanic and 83 Caucasian patients with confirmed IBD were analyzed. Hispanics were diagnosed with IBD at an older age than Caucasians (mean age 37.8 SD 16 vs. mean age 29.0 SD 14, P < 0.01). In Hispanics with IBD, there was a lower proportion of patients with CD compared to Caucasians with IBD (36% vs. 65%, P < 0.01). Although there were no significant differences in diagnostic examinations or medication prescription between the two groups, there was a higher number of bowel resections per patient in Caucasians compared with Hispanics (0.5 vs. 0.22, P = 0.01). CONCLUSIONS: Hispanics with IBD were diagnosed at a significantly older age than Caucasians and had a lower number of bowel resections per patient. In Hispanics with IBD, UC was more common than CD while CD was more common than UC among Caucasians with IBD. Further research is required to confirm these observations and determine if these findings reflect genetic or environmental differences.
Authors: Stephen B Hanauer; Brian G Feagan; Gary R Lichtenstein; Lloyd F Mayer; S Schreiber; Jean Frederic Colombel; Daniel Rachmilewitz; Douglas C Wolf; Allan Olson; Weihang Bao; Paul Rutgeerts Journal: Lancet Date: 2002-05-04 Impact factor: 79.321
Authors: Esther A Torres; Ramón De Jesús; Cynthia M Pérez; Michael Iñesta; Daniel Torres; Carlos Morell; Erica Just Journal: P R Health Sci J Date: 2003-09 Impact factor: 0.705
Authors: Bruce E Sands; Frank H Anderson; Charles N Bernstein; William Y Chey; Brian G Feagan; Richard N Fedorak; Michael A Kamm; Joshua R Korzenik; Bret A Lashner; Jane E Onken; Daniel Rachmilewitz; Paul Rutgeerts; Gary Wild; Douglas C Wolf; Paul A Marsters; Suzanne B Travers; Marion A Blank; Sander J van Deventer Journal: N Engl J Med Date: 2004-02-26 Impact factor: 91.245
Authors: Danny J Avalos; Antonio Mendoza-Ladd; Marc J Zuckerman; Mohammad Bashashati; Andres Alvarado; Alok Dwivedi; Oriana M Damas Journal: Dig Dis Sci Date: 2018-03-29 Impact factor: 3.199
Authors: Edward L Barnes; Bharati Kochar; Millie D Long; Christopher F Martin; Michael D Kappelman Journal: Inflamm Bowel Dis Date: 2017-12 Impact factor: 7.290
Authors: Kenechukwu Chudy-Onwugaje; Alexander P Mamunes; David A Schwartz; Sara Horst; Raymond K Cross Journal: Inflamm Bowel Dis Date: 2021-02-16 Impact factor: 5.325