| Literature DB >> 21393849 |
Valentina Zorzini1, Sarah Haesaerts, Niles P Donegan, Zhibiao Fu, Ambrose L Cheung, Nico A J van Nuland, Remy Loris.
Abstract
mazEF modules encode toxin-antitoxin pairs that are involved in the bacterial stress response through controlled and specific degradation of mRNA. Staphylococcus aureus MazF and MazE constitute a unique toxin-antitoxin module under regulation of the sigB operon. A MazF-type mRNA interferase is combined with an antitoxin of unknown fold. Crystals of S. aureus MazF (SaMazF) were grown in space group P2(1)2(1)2(1). The crystals diffracted to 2.1 Å resolution and are likely to contain two SaMazF dimers in the asymmetric unit.Entities:
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Year: 2011 PMID： 21393849 PMCID： PMC3053169 DOI： 10.1107/S1744309111000571
Source DB: PubMed Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun ISSN： 1744-3091