OBJECTIVES: To investigate whether infants with a score <50 on the Bayley Scales of Infant Development, Second Edition (BSID-II) demonstrated differences in functional ability, and to assess whether the Bayley Developmental Quotients (DQs) indicated such differences. STUDY DESIGN: Preterm infants (n = 67; 47 boys) with posthemorrhagic ventricular dilatation were evaluated at 25 months past term age using the BSID-II and grading of functional ability. Mental and Motor Bayley DQs were derived and compared with functional ability. RESULTS: Among the 34 subjects (51%) with a BSID-II score <50, there were clinically significant differences in the ability to walk, sit, eat, speak, and see. In all subjects, there were significant differences in Mental and Motor Bayley DQs based on grade of disability in each domain except hearing. CONCLUSIONS: Bayley DQ quantified the spread of functional ability in all children, provided a continuous parameter to compare ability in severely delayed children, and should be considered in future therapeutic trials of infants with brain injury.
OBJECTIVES: To investigate whether infants with a score <50 on the Bayley Scales of Infant Development, Second Edition (BSID-II) demonstrated differences in functional ability, and to assess whether the Bayley Developmental Quotients (DQs) indicated such differences. STUDY DESIGN: Preterm infants (n = 67; 47 boys) with posthemorrhagic ventricular dilatation were evaluated at 25 months past term age using the BSID-II and grading of functional ability. Mental and Motor Bayley DQs were derived and compared with functional ability. RESULTS: Among the 34 subjects (51%) with a BSID-II score <50, there were clinically significant differences in the ability to walk, sit, eat, speak, and see. In all subjects, there were significant differences in Mental and Motor Bayley DQs based on grade of disability in each domain except hearing. CONCLUSIONS: Bayley DQ quantified the spread of functional ability in all children, provided a continuous parameter to compare ability in severely delayed children, and should be considered in future therapeutic trials of infants with brain injury.
Authors: Jorien M Kerstjens; Ard Nijhuis; Christian V Hulzebos; Deirdre E van Imhoff; Aleid G van Wassenaer-Leemhuis; Ingrid C van Haastert; Enrico Lopriore; Titia Katgert; Renate M Swarte; Richard A van Lingen; Twan L Mulder; Céleste R Laarman; Katerina Steiner; Peter H Dijk Journal: PLoS One Date: 2015-07-20 Impact factor: 3.240
Authors: Tangunu Fosi; Carlton Chu; Wui Khean Chong; Chris Clark; Rod C Scott; Stewart Boyd; Michelle De Haan; Brian Neville Journal: Epilepsia Date: 2015-03-02 Impact factor: 5.864
Authors: Timo R de Haan; Loes Beckers; Rogier C J de Jonge; Lodewijk Spanjaard; Letty van Toledo; Dasja Pajkrt; Aleid G van Wassenaer-Leemhuis; Johanna H van der Lee Journal: PLoS One Date: 2013-03-18 Impact factor: 3.240