Literature DB >> 21392243

Bleeding per vaginam is associated with funisitis in women with preterm prelabour rupture of the fetal membranes.

C A Grotegut1, L N C Johnson, C B Fitzpatrick, R P Heine, G K Swamy, A P Murtha.   

Abstract

OBJECTIVE: To evaluate the risk of funisitis among women with preterm prelabour rupture of the membranes (PPROM) and subsequent bleeding per vaginam.
DESIGN: Prospective cohort study.
SETTING: A University Hospital in the USA. POPULATION: A total of 157 women with PPROM, divided into those with bleeding per vaginam during the hospital admission (n = 46) and those without bleeding per vaginam (n = 111).
METHODS: Pathologist blinded to bleeding status assessed placental pathology for funisitis. MAIN OUTCOME MEASURES: Funisitis.
RESULTS: Women with bleeding per vaginam were more likely to have funisitis (67.4% versus 36%, P < 0.001) compared with those without bleeding. Logistic regression demonstrated that bleeding per vaginam predicted funisitis after controlling for gestational age at admission, latency period and gestational age at delivery.
CONCLUSIONS: Among women with PPROM, those with bleeding per vaginam are more likely to have funisitis than those without bleeding per vaginam.
© 2011 The Authors BJOG An International Journal of Obstetrics and Gynaecology © 2011 RCOG.

Entities:  

Mesh:

Year:  2011        PMID: 21392243      PMCID: PMC3075338          DOI: 10.1111/j.1471-0528.2011.02911.x

Source DB:  PubMed          Journal:  BJOG        ISSN: 1470-0328            Impact factor:   6.531


  30 in total

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2.  Mechanisms of abruption-induced premature rupture of the fetal membranes: thrombin-enhanced interleukin-8 expression in term decidua.

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3.  Interleukin-6 concentrations in umbilical cord plasma are elevated in neonates with white matter lesions associated with periventricular leukomalacia.

Authors:  B H Yoon; R Romero; S H Yang; J K Jun; I O Kim; J H Choi; H C Syn
Journal:  Am J Obstet Gynecol       Date:  1996-05       Impact factor: 8.661

4.  Abruptio placentae and chorioamnionitis-microbiological and histologic correlation.

Authors:  A Rana; H Sawhney; S Gopalan; D Panigrahi; R Nijhawan
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5.  Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha), neonatal brain white matter lesions, and cerebral palsy.

Authors:  B H Yoon; J K Jun; R Romero; K H Park; R Gomez; J H Choi; I O Kim
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6.  A systemic fetal inflammatory response and the development of bronchopulmonary dysplasia.

Authors:  B H Yoon; R Romero; K S Kim; J S Park; S H Ki; B I Kim; J K Jun
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7.  Clinical significance of increasing histologic severity of acute inflammation in the fetal membranes and umbilical cord.

Authors:  K H van Hoeven; A Anyaegbunam; H Hochster; J E Whitty; J Distant; C Crawford; S M Factor
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Review 8.  Chorioamnionitis and labor.

Authors:  Rodney K Edwards
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9.  Proteomic biomarkers that predict the clinical success of rescue cerclage.

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10.  Idiopathic vaginal bleeding during pregnancy as the only clinical manifestation of intrauterine infection.

Authors:  Ricardo Gómez; Roberto Romero; Jyh Kae Nien; Luis Medina; Mario Carstens; Yeon Mee Kim; Tinnakorn Chaiworapongsa; Jimmy Espinoza; Rogelio González
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