OBJECTIVE: To study serum lipid profile in patients with cerebrovascular disease and to determine significant correlation between them. To ascertain the effect of age and sex on serum lipid profile. DESIGN: Case Control study. SETTING: Single Tertiary care centre in Southern India. PARTICIPANTS: Total of 100 patients of which 80 were cases of completed stroke (ischaemic--50 and haemorrhagic --30) and the remaining 20 were controls. Males accounted for 71 cases. All subjects were adult patients. Patients with suspected emboli of cardiac origin and diabetics (Type 1 and 2) were excluded from the study. None of the patients were on diet or other modification that would lower plasma lipid levels. RESULTS: 32 patients had elevated serum total cholesterol levels, of which 81.3% had ischaemic stroke and the rest haemorrhagic stroke. 10 patients had elevated serum triglyceride levels, of which 80% had ischaemic stroke and the rest haemorrhagic stroke. 33 patients had elevated serum low density lipoprotein levels of which 75.8% had ischaemic stroke whereas the remaining had haemorrhagic stroke. CONCLUSION: A statistically positive correlation was found between serum Total cholesterol, Triglycerides, LDL levels and the risk of stroke.
OBJECTIVE: To study serum lipid profile in patients with cerebrovascular disease and to determine significant correlation between them. To ascertain the effect of age and sex on serum lipid profile. DESIGN: Case Control study. SETTING: Single Tertiary care centre in Southern India. PARTICIPANTS: Total of 100 patients of which 80 were cases of completed stroke (ischaemic--50 and haemorrhagic --30) and the remaining 20 were controls. Males accounted for 71 cases. All subjects were adult patients. Patients with suspected emboli of cardiac origin and diabetics (Type 1 and 2) were excluded from the study. None of the patients were on diet or other modification that would lower plasma lipid levels. RESULTS: 32 patients had elevated serum total cholesterol levels, of which 81.3% had ischaemic stroke and the rest haemorrhagic stroke. 10 patients had elevated serum triglyceride levels, of which 80% had ischaemic stroke and the rest haemorrhagic stroke. 33 patients had elevated serum low density lipoprotein levels of which 75.8% had ischaemic stroke whereas the remaining had haemorrhagic stroke. CONCLUSION: A statistically positive correlation was found between serum Total cholesterol, Triglycerides, LDL levels and the risk of stroke.