Literature DB >> 2139118

Gingival hyperplasia in rats induced by oxodipine--a calcium channel blocker.

A Nyska1, T Waner, M Pirak, A Galiano, A Zlotogorski.   

Abstract

Oxodipine, a new calcium channel blocker, induced gingival hyperplasia in rats. This is the first time that a calcium channel blocker has been documented as resulting in gingival hyperplasia in rats. In contrast to diphenylhydantoin, the hyperplastic changes induced by oxodipine were not precipitated by any prior irritation. The histology consisted of purely fibroblastic proliferation without infiltrate of inflammatory cells.

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Year:  1990        PMID： 2139118     DOI： 10.1111/j.1600-0765.1990.tb00893.x

Source DB:  PubMed          Journal:  J Periodontal Res        ISSN： 0022-3484            Impact factor:   4.419


  3 in total

1.  Polarization microscopy of picrosirius red-stained collagen from oxodipine-induced hyperplastic gingiva of beagle dogs.

Authors:  D Dayan; T Waner; H Tal; A Nyska
Journal:  Int J Exp Pathol       Date:  1993-06       Impact factor: 1.925

2.  Nifedipine aggravates cyclosporine A-induced gingival hyperplasia.

Authors:  A Bökenkamp; B Bohnhorst; C Beier; N Albers; G Offner; J Brodehl
Journal:  Pediatr Nephrol       Date:  1994-04       Impact factor: 3.714

Review 3.  Calcium channel blocker-induced gingival enlargement.

Authors:  R Livada; J Shiloah
Journal:  J Hum Hypertens       Date:  2013-06-06       Impact factor: 3.012
  3 in total

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