Literature DB >> 21390714

Immortalization of human B-lymphocytes by epstein-barr virus.

P M Brickell1.   

Abstract

Epstein-Barr virus (EBV) is able to immortalize human B-lymphocytes with high efficiency. This property underlies the role of EBV in a number of human diseases. First, EBV is the causative agent of infectious mononucleosis, which is a benign proliferation of B-lymphocytes (1). Second, EBV is involved in the etiology of Burkitt's lymphoma (2) and of invasive B-lymphocyte proliferations found in immunosuppressed individuals (3).

Entities:  

Year:  1992        PMID： 21390714     DOI： 10.1385/0-89603-191-8:213

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  4 in total

1.  Detection and isolation of auto-reactive human antibodies from primary B cells.

Authors:  Victor G Sendra; Anthony Lie; Gabrielle Romain; Sandeep K Agarwal; Navin Varadarajan
Journal:  Methods       Date:  2013-06-26       Impact factor: 3.608

2.  Analysis of the genetic basis of periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome.

Authors:  Silvio Alessandro Di Gioia; Nicola Bedoni; Annette von Scheven-Gête; Federica Vanoni; Andrea Superti-Furga; Michaël Hofer; Carlo Rivolta
Journal:  Sci Rep       Date:  2015-05-19       Impact factor: 4.379

Review 3.  EBV Infection and Its Regulated Metabolic Reprogramming in Nasopharyngeal Tumorigenesis.

Authors:  Tingting Yang; Chanping You; Shuhui Meng; Zhengquan Lai; Weipeng Ai; Jun Zhang
Journal:  Front Cell Infect Microbiol       Date:  2022-07-01       Impact factor: 6.073

4.  The burden of trisomy 21 disrupts the proteostasis network in Down syndrome.

Authors:  Stefanos Aivazidis; Christina M Coughlan; Abhishek K Rauniyar; Hua Jiang; L Alexander Liggett; Kenneth N Maclean; James R Roede
Journal:  PLoS One       Date:  2017-04-21       Impact factor: 3.240
  4 in total

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