Literature DB >> 21388619

Effect of bevacizumab on postoperative adhesion formation in a rat uterine horn adhesion model and the correlation with vascular endothelial growth factor and Ki-67 immunopositivity.

Ozlem Moraloglu1, Hatice Işik, Sevtap Kiliç, Ulaş Sahin, Muzaffer Caydere, Hüseyin Ustün, Sertaç Batioglu.   

Abstract

We investigated whether adhesion formation is prevented by the inhibition of angiogenesis in a rat uterine horn adhesion model. A single-dose of bevacizumab was effective in preventing postoperative intraperitoneal adhesion formation among 30 Wistar albino rats that underwent serosal injury by use of a standard technique after laparotomy with intraperitoneal bevacizumab.
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 21388619     DOI： 10.1016/j.fertnstert.2011.02.005

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  6 in total

1.  Postoperative peritoneal adhesion: an update on physiopathology and novel traditional herbal and modern medical therapeutics.

Authors:  Setareh Soltany
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2020-09-26       Impact factor: 3.000

2.  Prevention of peritoneal adhesions using polymeric rheological blends.

Authors:  Todd Hoare; Yoon Yeo; Evangelia Bellas; Joost P Bruggeman; Daniel S Kohane
Journal:  Acta Biomater       Date:  2013-12-21       Impact factor: 8.947

3.  The effect of antivascular endothelial growth factor on the development of adhesion formation in laparotomized rats: experimental study.

Authors:  Murat Basbug; Nurullah Bulbuller; Cemalettin Camci; Refik Ayten; Erhan Aygen; Ibrahim Hanifi Ozercan; Zulfu Arikanoglu; Sami Akbulut
Journal:  Gastroenterol Res Pract       Date:  2011-06-28       Impact factor: 2.260

4.  A novel angiogenesis inhibitor bevacizumab induces apoptosis in the rat endometriosis model.

Authors:  D Soysal; S Kızıldağ; B Saatlı; C Posacı; S Soysal; M Koyuncuoğlu; Öe Doğan
Journal:  Balkan J Med Genet       Date:  2015-04-10       Impact factor: 0.519

Review 5.  A systemic review of randomized controlled studies about prevention with pharmacologic agents of adhesion formation in the rat uterine horn model.

Authors:  Gokalp Oner; Pasa Ulug
Journal:  Arch Med Sci       Date:  2015-01-14       Impact factor: 3.318

Review 6.  Efficacy of Anti-VEGF/VEGFR Agents on Animal Models of Endometriosis: A Systematic Review and Meta-Analysis.

Authors:  Shuangge Liu; Xiaoyan Xin; Teng Hua; Rui Shi; Shuqi Chi; Zhishan Jin; Hongbo Wang
Journal:  PLoS One       Date:  2016-11-17       Impact factor: 3.240
  6 in total

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