| Literature DB >> 21388182 |
Sara P Morcillo1, Luis Álvarez de Cienfuegos, Antonio J Mota, José Justicia, Rafael Robles.
Abstract
A mild method for the selective esterification of primary alcohols is described. The use of different phosphines, I(2), and imidazole allows the selective esterification of a wide variety of acids with excellent results. The generation of a bulky phosphonium-carboxylate salt as intermediate could justify the selectivity observed in this process. Additionally, amides also can be synthesized with use of this method.Entities:
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Year: 2011 PMID： 21388182 DOI： 10.1021/jo102395c
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354