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Literature DB >> 21387497

One-pot high-yielding synthesis of the DPP4-selective inhibitor ABT-341 by a four-component coupling mediated by a diphenylprolinol silyl ether.

Hayato Ishikawa¹, Masakazu Honma, Yujiro Hayashi.

Abstract

Entities: Chemical Gene

Year: 2011 PMID： 21387497 DOI： 10.1002/anie.201006204

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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11 in total

1. Modular Synthesis of Novel Macrocycles Bearing α,β-Unsaturated Chemotypes through a Series of One-Pot, Sequential Protocols.

Authors: Salim Javed; Mahipal Bodugam; Jessica Torres; Arghya Ganguly; Paul R Hanson
Journal: Chemistry Date: 2016-04-05 Impact factor: 5.236

2. Rapid, scalable assembly of stereochemically rich, mono- and bicyclic acyl sultams.

Authors: Naeem Asad; Thiwanka B Samarakoon; Qin Zang; Joanna K Loh; Salim Javed; Paul R Hanson
Journal: Org Lett Date: 2013-12-06 Impact factor: 6.005

3. An efficient, modular approach for the synthesis of (+)-strictifolione and a related natural product.

Authors: Susanthi Jayasinghe; Phanindra K M Venukadasula; Paul R Hanson
Journal: Org Lett Date: 2013-12-02 Impact factor: 6.005

4. A phosphate tether-mediated, one-pot, sequential ring-closing metathesis/cross-metathesis/chemoselective hydrogenation protocol.

Authors: Phanindra K M Venukadasula; Rambabu Chegondi; Gregory M Suryn; Paul R Hanson
Journal: Org Lett Date: 2012-05-08 Impact factor: 6.005

One-pot high-yielding synthesis of the DPP4-selective inhibitor ABT-341 by a four-component coupling mediated by a diphenylprolinol silyl ether.

1. Modular Synthesis of Novel Macrocycles Bearing α,β-Unsaturated Chemotypes through a Series of One-Pot, Sequential Protocols.

2. Rapid, scalable assembly of stereochemically rich, mono- and bicyclic acyl sultams.

3. An efficient, modular approach for the synthesis of (+)-strictifolione and a related natural product.

4. A phosphate tether-mediated, one-pot, sequential ring-closing metathesis/cross-metathesis/chemoselective hydrogenation protocol.

5. A Pot-Economical Approach to the Total Synthesis of Sch-725674.

6. A modular phosphate tether-mediated divergent strategy to complex polyols.

7. One-pot synthesis of (-)-Ambrox.

8. Pot economy and one-pot synthesis.

9. Markovnikov-addition of H-phosphonates to terminal alkynes under metal- and solvent-free conditions.

10. Pot and time economies in the total synthesis of Corey lactone.