| Literature DB >> 21387054 |
Ziyang Hao1, Yanqun Song, Shixian Lin, Maiyun Yang, Yujie Liang, Jing Wang, Peng R Chen.
Abstract
A concise route was developed for the facile synthesis of a cyclic pyrrolysine analogue bearing an azide handle. Directed evolution enabled the encoding of this non-natural amino acid in both prokaryotic and eukaryotic cells, which offers a highly efficient approach for the site-specific protein labeling using click chemistry. © The Royal Society of Chemistry 2011Entities:
Mesh：
Substances：
Year: 2011 PMID： 21387054 DOI： 10.1039/c1cc00024a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222