Literature DB >> 21385733

Pathophysiological relevance of proteomics investigations of drug-induced hepatotoxicity in HepG2 cells.

Hartmut Jaeschke, Mitchell R McGill, Anup Ramachandran.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21385733      PMCID： PMC6280871          DOI： 10.1093/toxsci/kfr053

Source DB:  PubMed          Journal:  Toxicol Sci        ISSN： 1096-0929            Impact factor:   4.849


× No keyword cloud information.
  21 in total

Review 1.  Molecular mechanisms of the hepatotoxicity caused by acetaminophen.

Authors:  S D Nelson
Journal:  Semin Liver Dis       Date:  1990-11       Impact factor: 6.115

2.  Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection.

Authors:  Kenneth L Muldrew; Laura P James; Leslie Coop; Sandra S McCullough; Howard P Hendrickson; Jack A Hinson; Philip R Mayeux
Journal:  Drug Metab Dispos       Date:  2002-04       Impact factor: 3.922

3.  Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo.

Authors:  D J Jollow; J R Mitchell; W Z Potter; D C Davis; J R Gillette; B B Brodie
Journal:  J Pharmacol Exp Ther       Date:  1973-10       Impact factor: 4.030

4.  Acetaminophen induces a caspase-dependent and Bcl-XL sensitive apoptosis in human hepatoma cells and lymphocytes.

Authors:  A Hamid Boulares; Anna J Zoltoski; Bogdan A Stoica; Olivier Cuvillier; Mark E Smulson
Journal:  Pharmacol Toxicol       Date:  2002-01

5.  Effects of dimethylsulfoxide on metabolism and toxicity of acetaminophen in mice.

Authors:  Mi Young Yoon; Sun Ju Kim; Byung-Hoon Lee; Jin-Ho Chung; Young Chul Kim
Journal:  Biol Pharm Bull       Date:  2006-08       Impact factor: 2.233

6.  The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes.

Authors:  Hui-Min Yan; Anup Ramachandran; Mary Lynn Bajt; John J Lemasters; Hartmut Jaeschke
Journal:  Toxicol Sci       Date:  2010-07-08       Impact factor: 4.849

7.  Cytotoxic effects of 110 reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells. II mechanistic assays on NAD(P)H, ATP and DNA contents.

Authors:  Willem G E J Schoonen; Jeroen A D M de Roos; Walter M A Westerink; Eric Débiton
Journal:  Toxicol In Vitro       Date:  2005-06       Impact factor: 3.500

8.  Measurement of serum acetaminophen-protein adducts in patients with acute liver failure.

Authors:  Timothy J Davern; Laura P James; Jack A Hinson; Julie Polson; Anne M Larson; Robert J Fontana; Ezmina Lalani; Santiago Munoz; A Obaid Shakil; William M Lee
Journal:  Gastroenterology       Date:  2006-03       Impact factor: 22.682

9.  Acetaminophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: protection by N-acetyl cysteine.

Authors:  Mary Lynn Bajt; Tamara R Knight; John J Lemasters; Hartmut Jaeschke
Journal:  Toxicol Sci       Date:  2004-04-28       Impact factor: 4.849

10.  Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells.

Authors:  Y Dai; A I Cederbaum
Journal:  J Pharmacol Exp Ther       Date:  1995-06       Impact factor: 4.030
View more
  3 in total

Review 1.  Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

Authors:  Patricio Godoy; Nicola J Hewitt; Ute Albrecht; Melvin E Andersen; Nariman Ansari; Sudin Bhattacharya; Johannes Georg Bode; Jennifer Bolleyn; Christoph Borner; Jan Böttger; Albert Braeuning; Robert A Budinsky; Britta Burkhardt; Neil R Cameron; Giovanni Camussi; Chong-Su Cho; Yun-Jaie Choi; J Craig Rowlands; Uta Dahmen; Georg Damm; Olaf Dirsch; María Teresa Donato; Jian Dong; Steven Dooley; Dirk Drasdo; Rowena Eakins; Karine Sá Ferreira; Valentina Fonsato; Joanna Fraczek; Rolf Gebhardt; Andrew Gibson; Matthias Glanemann; Chris E P Goldring; María José Gómez-Lechón; Geny M M Groothuis; Lena Gustavsson; Christelle Guyot; David Hallifax; Seddik Hammad; Adam Hayward; Dieter Häussinger; Claus Hellerbrand; Philip Hewitt; Stefan Hoehme; Hermann-Georg Holzhütter; J Brian Houston; Jens Hrach; Kiyomi Ito; Hartmut Jaeschke; Verena Keitel; Jens M Kelm; B Kevin Park; Claus Kordes; Gerd A Kullak-Ublick; Edward L LeCluyse; Peng Lu; Jennifer Luebke-Wheeler; Anna Lutz; Daniel J Maltman; Madlen Matz-Soja; Patrick McMullen; Irmgard Merfort; Simon Messner; Christoph Meyer; Jessica Mwinyi; Dean J Naisbitt; Andreas K Nussler; Peter Olinga; Francesco Pampaloni; Jingbo Pi; Linda Pluta; Stefan A Przyborski; Anup Ramachandran; Vera Rogiers; Cliff Rowe; Celine Schelcher; Kathrin Schmich; Michael Schwarz; Bijay Singh; Ernst H K Stelzer; Bruno Stieger; Regina Stöber; Yuichi Sugiyama; Ciro Tetta; Wolfgang E Thasler; Tamara Vanhaecke; Mathieu Vinken; Thomas S Weiss; Agata Widera; Courtney G Woods; Jinghai James Xu; Kathy M Yarborough; Jan G Hengstler
Journal:  Arch Toxicol       Date:  2013-08-23       Impact factor: 5.153

2.  Extending the limits of quantitative proteome profiling with data-independent acquisition and application to acetaminophen-treated three-dimensional liver microtissues.

Authors:  Roland Bruderer; Oliver M Bernhardt; Tejas Gandhi; Saša M Miladinović; Lin-Yang Cheng; Simon Messner; Tobias Ehrenberger; Vito Zanotelli; Yulia Butscheid; Claudia Escher; Olga Vitek; Oliver Rinner; Lukas Reiter
Journal:  Mol Cell Proteomics       Date:  2015-02-27       Impact factor: 5.911

3.  Selection of Suitable Reference Genes for qPCR Gene Expression Analysis of HepG2 and L02 in Four Different Liver Cell Injured Models.

Authors:  Jiyu Chen; Zhenzhen Bao; Yanli Huang; Zhenglong Wang; Yucheng Zhao
Journal:  Biomed Res Int       Date:  2020-07-14       Impact factor: 3.411
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.