| Literature DB >> 21384858 |
Edward T Castellana1, Roberto C Gamez, David H Russell.
Abstract
The fabrication of a label-free mass spectrometry and optical detection-based biosensor platform for the detection of low-abundance lipophilic analytes in complex mixtures is described. The biosensor consists of a lipid layer partially tethered to the surface of a gold nanorod. The effectiveness of the biosensor is demonstrated for the label-free detection of a lipophilic drug in aqueous solution and a lipopeptide in serum.Entities:
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Year: 2011 PMID: 21384858 DOI: 10.1021/ja109936h
Source DB: PubMed Journal: J Am Chem Soc ISSN: 0002-7863 Impact factor: 15.419