| Literature DB >> 21384845 |
Na Zeng1, Yang Shen, Ling-Zhi Li, Wei-Hua Jiao, Pin-Yi Gao, Shao-Jiang Song, Wan-Sheng Chen, Hou-Wen Lin.
Abstract
Bioassay-guided fractionation of an EtOAc extract of the leaves of Rosa laevigata afforded two new 19-oxo-18,19-seco-ursane-type triterpenes (1 and 3), a new ursane-type nortriterpene (2), a new ursane-type triterpene lactone saponin (4), and two new oleanane-type triterpenoids (5 and 6), together with eight known triterpenoids (7-14). Compound 1, a 19-oxo-18,19-seco-28-norursane, possesses a conjugated diene between C-12 and C-17. Several of the isolated compounds (1, 5, 7, 11, and 13) exhibited moderate activities in anti-inflammatory assays in vitro.Entities:
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Year: 2011 PMID: 21384845 DOI: 10.1021/np1007922
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050