| Literature DB >> 21384824 |
Tarun K Pradhan1, K Syam Krishnan, Jean-Luc Vasse, Jan Szymoniak.
Abstract
An asymmetric variant of the hydrozirconation reaction has been established starting from Boc-protected chiral allylic amines. The resulting diastereoselectively formed N-functionalized organozirconiums can be considered as promising chirons. In this case, they have been transformed into enantiomerically enriched cis-2,3-disubstituted azetidines through a iodination/cyclization sequence.Entities:
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Year: 2011 PMID： 21384824 DOI： 10.1021/ol200323r
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005