Literature DB >> 2138414

Maternal serum Down syndrome screening: unconjugated estriol is not useful.

J N Macri1, R V Kasturi, D A Krantz, E J Cook, S G Sunderji, J W Larsen.   

Abstract

Study of 41 known Down syndrome cases and 441 matched controls did not confirm earlier reports that low unconjugated estriol levels can be used to detect fetal Down syndrome. Hence the obstetric community should exercise caution in using unconjugated estriol levels as a marker in prenatal Down syndrome screening.

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Year:  1990        PMID: 2138414     DOI: 10.1016/0002-9378(90)90980-l

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  4 in total

1.  Antenatal screening for Down's syndrome.

Authors:  N Leporrier; M Herrou; P Leymarie
Journal:  BMJ       Date:  1992-10-24

2.  Prenatal screening for Down's syndrome.

Authors: 
Journal:  BMJ       Date:  1991-09-21

3.  Software for screening to assess risk of Down's syndrome.

Authors:  T M Reynolds
Journal:  BMJ       Date:  1991-04-20

Review 4.  Down's syndrome screening: a controversial test, with more controversy to come!

Authors:  T M Reynolds
Journal:  J Clin Pathol       Date:  2000-12       Impact factor: 3.411

  4 in total

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