Literature DB >> 21383270

The window of opportunity for treatment withdrawal.

Dominic Wilkinson1.   

Abstract

Physicians sometimes refer to a "window of opportunity" for withdrawing life-sustaining treatment in patients with acute severe brain injury. There is a period of critical illness and physiological instability when treatment withdrawal is likely to be followed by death but prognosis is uncertain. If decisions are delayed, greater prognostic certainty can be achieved, but with the risk that the patient is no longer dependent on life support and survives with very severe disability. In this article I draw on the example of birth asphyxia and highlight the role that the window of opportunity sometimes plays in decisions about life-sustaining treatment in intensive care. I outline the potential arguments in favor of and against taking the window into account. I argue that it is, at least sometimes, ethical and appropriate for physicians and parents to be influenced by the window of opportunity in their decisions about life-sustaining treatment.

Entities:  

Mesh:

Year:  2011        PMID: 21383270     DOI: 10.1001/archpediatrics.2011.4

Source DB:  PubMed          Journal:  Arch Pediatr Adolesc Med        ISSN: 1072-4710


  6 in total

1.  Characterization of Death in Neonatal Encephalopathy in the Hypothermia Era.

Authors:  Monica E Lemmon; Renee D Boss; Sonia L Bonifacio; Audrey Foster-Barber; A James Barkovich; Hannah C Glass
Journal:  J Child Neurol       Date:  2016-12-20       Impact factor: 1.987

2.  Integrating neurocritical care approaches into neonatology: should all infants be treated equitably?

Authors:  P C Mann; S M Gospe; K J Steinman; B S Wilfond
Journal:  J Perinatol       Date:  2015-08-06       Impact factor: 2.521

3.  A good resource for parents, but will clinicians use it?: Evaluation of a resource for paediatric end-of-life decision making.

Authors:  Clare Delany; Vicki Xafis; Lynn Gillam; Jo-Anne Hughson; Jenny Hynson; Dominic Wilkinson
Journal:  BMC Palliat Care       Date:  2017-01-25       Impact factor: 3.234

4.  Cerebrospinal fluid levels of neuron-specific enolase predict the severity of brain damage in newborns with neonatal hypoxic-ischemic encephalopathy treated with hypothermia.

Authors:  Marisol-Zulema León-Lozano; Juan Arnaez; Ana Valls; Gemma Arca; Thais Agut; Ana Alarcón; Alfredo Garcia-Alix
Journal:  PLoS One       Date:  2020-06-01       Impact factor: 3.240

5.  Discussing brain magnetic resonance imaging results for neonates with hypoxic-ischemic encephalopathy treated with hypothermia: A challenge for clinicians and parents.

Authors:  Ariel Cascio; Amaryllis Ferrand; Eric Racine; Marie St-Hilaire; Priscille-Nice Sanon; Andreea Gorgos; Pia Wintermark
Journal:  eNeurologicalSci       Date:  2022-09-11

6.  Early identification of brain injury in infants with hypoxic ischemic encephalopathy at high risk for severe impairments: accuracy of MRI performed in the first days of life.

Authors:  Thais Agut; Marisol León; Mónica Rebollo; Jordi Muchart; Gemma Arca; Alfredo Garcia-Alix
Journal:  BMC Pediatr       Date:  2014-07-08       Impact factor: 2.125

  6 in total

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