Literature DB >> 21378973

Exocytosis at the hair cell ribbon synapse apparently operates without neuronal SNARE proteins.

Régis Nouvian1, Jakob Neef, Anna V Bulankina, Ellen Reisinger, Tina Pangršič, Thomas Frank, Stefan Sikorra, Nils Brose, Thomas Binz, Tobias Moser.   

Abstract

SNARE proteins mediate membrane fusion. Neurosecretion depends on neuronal soluble NSF attachment protein receptors (SNAREs; SNAP-25, syntaxin-1, and synaptobrevin-1 or synaptobrevin-2) and is blocked by neurotoxin-mediated cleavage or genetic ablation. We found that exocytosis in mouse inner hair cells (IHCs) was insensitive to neurotoxins and genetic ablation of neuronal SNAREs. mRNA, but no synaptically localized protein, of neuronal SNAREs was present in IHCs. Thus, IHC exocytosis is unconventional and may operate independently of neuronal SNAREs.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21378973     DOI： 10.1038/nn.2774

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN： 1097-6256            Impact factor:   24.884


  15 in total

1.  Calcium dependence of exocytosis and endocytosis at the cochlear inner hair cell afferent synapse.

Authors:  D Beutner; T Voets; E Neher; T Moser
Journal:  Neuron       Date:  2001-03       Impact factor: 17.173

2.  Kinetics of exocytosis and endocytosis at the cochlear inner hair cell afferent synapse of the mouse.

Authors:  T Moser; D Beutner
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-18       Impact factor: 11.205

3.  SNARE complex at the ribbon synapses of cochlear hair cells: analysis of synaptic vesicle- and synaptic membrane-associated proteins.

Authors:  S Safieddine; R J Wenthold
Journal:  Eur J Neurosci       Date:  1999-03       Impact factor: 3.386

4.  Hair cell synaptic ribbons are essential for synchronous auditory signalling.

Authors:  Darina Khimich; Régis Nouvian; Rémy Pujol; Susanne Tom Dieck; Alexander Egner; Eckart D Gundelfinger; Tobias Moser
Journal:  Nature       Date:  2005-04-14       Impact factor: 49.962

5.  v-SNAREs control exocytosis of vesicles from priming to fusion.

Authors:  Maria Borisovska; Ying Zhao; Yaroslav Tsytsyura; Nataliya Glyvuk; Shigeo Takamori; Ulf Matti; Jens Rettig; Thomas Südhof; Dieter Bruns
Journal:  EMBO J       Date:  2005-05-26       Impact factor: 11.598

6.  Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins.

Authors:  G Miesenböck; D A De Angelis; J E Rothman
Journal:  Nature       Date:  1998-07-09       Impact factor: 49.962

7.  A null mutation in VAMP1/synaptobrevin is associated with neurological defects and prewean mortality in the lethal-wasting mouse mutant.

Authors:  Arne M Nystuen; Jamie K Schwendinger; Andrew J Sachs; Andy W Yang; Neena B Haider
Journal:  Neurogenetics       Date:  2006-11-11       Impact factor: 2.660

8.  Unique substrate recognition by botulinum neurotoxins serotypes A and E.

Authors:  Sheng Chen; Joseph T Barbieri
Journal:  J Biol Chem       Date:  2006-02-14       Impact factor: 5.157

9.  Complexin-I is required for high-fidelity transmission at the endbulb of Held auditory synapse.

Authors:  Nicola Strenzke; Soham Chanda; Cornelia Kopp-Scheinpflug; Darina Khimich; Kerstin Reim; Anna V Bulankina; Andreas Neef; Fred Wolf; Nils Brose; Matthew A Xu-Friedman; Tobias Moser
Journal:  J Neurosci       Date:  2009-06-24       Impact factor: 6.167

Review 10.  Neurotoxins affecting neuroexocytosis.

Authors:  G Schiavo; M Matteoli; C Montecucco
Journal:  Physiol Rev       Date:  2000-04       Impact factor: 37.312
View more
  48 in total

1.  Ca(2+) influx and neurotransmitter release at ribbon synapses.

Authors:  Soyoun Cho; Henrique von Gersdorff
Journal:  Cell Calcium       Date:  2012-07-08       Impact factor: 6.817

Review 2.  Presynaptic active zones in invertebrates and vertebrates.

Authors:  Frauke Ackermann; Clarissa L Waites; Craig C Garner
Journal:  EMBO Rep       Date:  2015-07-09       Impact factor: 8.807

3.  Endophilin-A regulates presynaptic Ca2+ influx and synaptic vesicle recycling in auditory hair cells.

Authors:  Jana Kroll; Lina M Jaime Tobón; Christian Vogl; Jakob Neef; Ilona Kondratiuk; Melanie König; Nicola Strenzke; Carolin Wichmann; Ira Milosevic; Tobias Moser
Journal:  EMBO J       Date:  2019-02-07       Impact factor: 11.598

Review 4.  Voltage-Gated Calcium Channels: Key Players in Sensory Coding in the Retina and the Inner Ear.

Authors:  Tina Pangrsic; Joshua H Singer; Alexandra Koschak
Journal:  Physiol Rev       Date:  2018-10-01       Impact factor: 37.312

5.  Efferent innervation of turtle semicircular canal cristae: comparisons with bird and mouse.

Authors:  Paivi M Jordan; Margaret Fettis; Joseph C Holt
Journal:  J Comp Neurol       Date:  2015-03-25       Impact factor: 3.215

6.  Calcium-induced calcium release supports recruitment of synaptic vesicles in auditory hair cells.

Authors:  Manuel Castellano-Muñoz; Michael E Schnee; Anthony J Ricci
Journal:  J Neurophysiol       Date:  2015-10-28       Impact factor: 2.714

Review 7.  Morphological and physiological development of auditory synapses.

Authors:  Wei-Ming Yu; Lisa V Goodrich
Journal:  Hear Res       Date:  2014-02-05       Impact factor: 3.208

Review 8.  Ribbon synapses in zebrafish hair cells.

Authors:  T Nicolson
Journal:  Hear Res       Date:  2015-04-25       Impact factor: 3.208

9.  Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses.

Authors:  Didier Dulon; Saaid Safieddine; Christine Petit; Nicolas Michalski; Juan D Goutman; Sarah Marie Auclair; Jacques Boutet de Monvel; Margot Tertrais; Alice Emptoz; Alexandre Parrin; Sylvie Nouaille; Marc Guillon; Martin Sachse; Danica Ciric; Amel Bahloul; Jean-Pierre Hardelin; Roger Bryan Sutton; Paul Avan; Shyam S Krishnakumar; James E Rothman
Journal:  Elife       Date:  2017-11-07       Impact factor: 8.140

10.  Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing.

Authors:  Christian Vogl; Iliana Panou; Gulnara Yamanbaeva; Carolin Wichmann; Sara J Mangosing; Fabio Vilardi; Artur A Indzhykulian; Tina Pangršič; Rosamaria Santarelli; Montserrat Rodriguez-Ballesteros; Thomas Weber; Sangyong Jung; Elena Cardenas; Xudong Wu; Sonja M Wojcik; Kelvin Y Kwan; Ignacio Del Castillo; Blanche Schwappach; Nicola Strenzke; David P Corey; Shuh-Yow Lin; Tobias Moser
Journal:  EMBO J       Date:  2016-07-25       Impact factor: 11.598
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.