Literature DB >> 21378947

Protein-protein interactions: making drug design second nature.

Dan L Sackett, David Sept.   

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Year:  2009        PMID： 21378947     DOI： 10.1038/nchem.427

Source DB:  PubMed          Journal:  Nat Chem        ISSN： 1755-4330            Impact factor:   24.427


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  8 in total

1.  Development of small molecules designed to modulate protein-protein interactions.

Authors:  Ye Che; Bernard R Brooks; Garland R Marshall
Journal:  J Comput Aided Mol Des       Date:  2006-04-19       Impact factor: 3.686

Review 2.  Computational identification of inhibitors of protein-protein interactions.

Authors:  Shijun Zhong; Alba T Macias; Alexander D MacKerell
Journal:  Curr Top Med Chem       Date:  2007       Impact factor: 3.295

Review 3.  Targeting protein-protein interactions with small molecules: challenges and perspectives for computational binding epitope detection and ligand finding.

Authors:  Domingo González-Ruiz; Holger Gohlke
Journal:  Curr Med Chem       Date:  2006       Impact factor: 4.530

Review 4.  Protein-protein interaction inhibitors: small molecules from screening techniques.

Authors:  Steven Fletcher; Andrew D Hamilton
Journal:  Curr Top Med Chem       Date:  2007       Impact factor: 3.295

Review 5.  Peptidic modulators of protein-protein interactions: progress and challenges in computational design.

Authors:  Mor Rubinstein; Masha Y Niv
Journal:  Biopolymers       Date:  2009-07       Impact factor: 2.505

Review 6.  The design, structures and therapeutic potential of protein epitope mimetics.

Authors:  John A Robinson; Steve Demarco; Frank Gombert; Kerstin Moehle; Daniel Obrecht
Journal:  Drug Discov Today       Date:  2008-09-11       Impact factor: 7.851

7.  In silico design of tubulin-targeted antimitotic peptides.

Authors:  Stefano Pieraccini; Giorgio Saladino; Graziella Cappelletti; Daniele Cartelli; Pierangelo Francescato; Giovanna Speranza; Paolo Manitto; Maurizio Sironi
Journal:  Nat Chem       Date:  2009-10-23       Impact factor: 24.427

Review 8.  Efficacy of selected natural products as therapeutic agents against cancer.

Authors:  Sanjeev Banerjee; Zhiwei Wang; Mussop Mohammad; Fazlul H Sarkar; Ramzi M Mohammad
Journal:  J Nat Prod       Date:  2008-02-27       Impact factor: 4.050
  8 in total
  6 in total

1.  Targeting the lateral interactions of transmembrane domain 5 of Epstein-Barr virus latent membrane protein 1.

Authors:  Xiaohui Wang; Jonel P Saludes; Tina X Zhao; Adam Csakai; Zeno Fiorini; Sherry A Chavez; Jing Li; Gui-in Lee; Krisztina Varga; Hang Yin
Journal:  Biochim Biophys Acta       Date:  2012-05-17

2.  Rational design of small-molecule stabilizers of spermine synthase dimer by virtual screening and free energy-based approach.

Authors:  Zhe Zhang; Virginie Martiny; David Lagorce; Yoshihiko Ikeguchi; Emil Alexov; Maria A Miteva
Journal:  PLoS One       Date:  2014-10-23       Impact factor: 3.240

3.  Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).

Authors:  Georgia Melagraki; Evangelos Ntougkos; Vagelis Rinotas; Christos Papaneophytou; Georgios Leonis; Thomas Mavromoustakos; George Kontopidis; Eleni Douni; Antreas Afantitis; George Kollias
Journal:  PLoS Comput Biol       Date:  2017-04-20       Impact factor: 4.475

4.  In Silico Discovery of Plant-Origin Natural Product Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).

Authors:  Georgia Melagraki; Evangelos Ntougkos; Dimitra Papadopoulou; Vagelis Rinotas; Georgios Leonis; Eleni Douni; Antreas Afantitis; George Kollias
Journal:  Front Pharmacol       Date:  2018-07-25       Impact factor: 5.810

5.  Repositioning antimicrobial agent pentamidine as a disruptor of the lateral interactions of transmembrane domain 5 of EBV latent membrane protein 1.

Authors:  Xiaohui Wang; Zeno Fiorini; Christina Smith; Yingning Zhang; Jing Li; Linda R Watkins; Hang Yin
Journal:  PLoS One       Date:  2012-10-19       Impact factor: 3.240

6.  PepComposer: computational design of peptides binding to a given protein surface.

Authors:  Agnieszka Obarska-Kosinska; Alfredo Iacoangeli; Rosalba Lepore; Anna Tramontano
Journal:  Nucleic Acids Res       Date:  2016-04-30       Impact factor: 16.971
  6 in total

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