Literature DB >> 21378186

Whole-genome sequencing of Staphylococcus aureus strain RN4220, a key laboratory strain used in virulence research, identifies mutations that affect not only virulence factors but also the fitness of the strain.

Dhanalakshmi Nair1, Guido Memmi, David Hernandez, Jonathan Bard, Marie Beaume, Steven Gill, Patrice Francois, Ambrose L Cheung.   

Abstract

Staphylococcus aureus RN4220, a cloning intermediate, is sometimes used in virulence, resistance, and metabolic studies. Using whole-genome sequencing, we showed that RN4220 differs from NCTC8325 and contains a number of genetic polymorphisms that affect both virulence and general fitness, implying a need for caution in using this strain for such studies.

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Year:  2011        PMID： 21378186      PMCID： PMC3133102          DOI： 10.1128/JB.00027-11

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  27 in total

1.  Orientation and expression of methicillin-resistant Staphylococcus aureus small RNAs by direct multiplexed measurements using the nCounter of NanoString technology.

Authors:  Marie Beaume; David Hernandez; Mylène Docquier; Céline Delucinge-Vivier; Patrick Descombes; Patrice François
Journal:  J Microbiol Methods       Date:  2010-12-31       Impact factor: 2.363

Review 2.  Prokaryotic nucleotide excision repair: the UvrABC system.

Authors:  James J Truglio; Deborah L Croteau; Bennett Van Houten; Caroline Kisker
Journal:  Chem Rev       Date:  2006-02       Impact factor: 60.622

3.  sar Genetic determinants necessary for transcription of RNAII and RNAIII in the agr locus of Staphylococcus aureus.

Authors:  A L Cheung; M G Bayer; J H Heinrichs
Journal:  J Bacteriol       Date:  1997-06       Impact factor: 3.490

4.  EsxA and EsxB are secreted by an ESAT-6-like system that is required for the pathogenesis of Staphylococcus aureus infections.

Authors:  Monica L Burts; Wade A Williams; Kristin DeBord; Dominique M Missiakas
Journal:  Proc Natl Acad Sci U S A       Date:  2005-01-18       Impact factor: 11.205

5.  Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain.

Authors:  Steven R Gill; Derrick E Fouts; Gordon L Archer; Emmanuel F Mongodin; Robert T Deboy; Jacques Ravel; Ian T Paulsen; James F Kolonay; Lauren Brinkac; Mauren Beanan; Robert J Dodson; Sean C Daugherty; Ramana Madupu; Samuel V Angiuoli; A Scott Durkin; Daniel H Haft; Jessica Vamathevan; Hoda Khouri; Terry Utterback; Chris Lee; George Dimitrov; Lingxia Jiang; Haiying Qin; Jan Weidman; Kevin Tran; Kathy Kang; Ioana R Hance; Karen E Nelson; Claire M Fraser
Journal:  J Bacteriol       Date:  2005-04       Impact factor: 3.490

6.  The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage.

Authors:  B N Kreiswirth; S Löfdahl; M J Betley; M O'Reilly; P M Schlievert; M S Bergdoll; R P Novick
Journal:  Nature       Date:  1983 Oct 20-26       Impact factor: 49.962

7.  Staphylococcus aureus induces platelet aggregation via a fibrinogen-dependent mechanism which is independent of principal platelet glycoprotein IIb/IIIa fibrinogen-binding domains.

Authors:  A S Bayer; P M Sullam; M Ramos; C Li; A L Cheung; M R Yeaman
Journal:  Infect Immun       Date:  1995-09       Impact factor: 3.441

8.  Molecular characterization of the clumping factor (fibrinogen receptor) of Staphylococcus aureus.

Authors:  D McDevitt; P Francois; P Vaudaux; T J Foster
Journal:  Mol Microbiol       Date:  1994-01       Impact factor: 3.501

9.  Characterizing the effect of the Staphylococcus aureus virulence factor regulator, SarA, on log-phase mRNA half-lives.

Authors:  Corbette Roberts; Kelsi L Anderson; Ellen Murphy; Steven J Projan; William Mounts; Barry Hurlburt; Mark Smeltzer; Ross Overbeek; Terrence Disz; Paul M Dunman
Journal:  J Bacteriol       Date:  2006-04       Impact factor: 3.490

10.  A slipped-mispairing mutation in AgrA of laboratory strains and clinical isolates results in delayed activation of agr and failure to translate delta- and alpha-haemolysins.

Authors:  Katrina Traber; Richard Novick
Journal:  Mol Microbiol       Date:  2006-03       Impact factor: 3.501
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  84 in total

1.  Enhancement of the pathogenicity of Staphylococcus aureus strain Newman by a small noncoding RNA SprX1.

Authors:  Manikandan Kathirvel; Hasmatbanu Buchad; Mrinalini Nair
Journal:  Med Microbiol Immunol       Date:  2016-07-20       Impact factor: 3.402

2.  Antibiotics Stimulate Formation of Vesicles in Staphylococcus aureus in both Phage-Dependent and -Independent Fashions and via Different Routes.

Authors:  Federica Andreoni; Masanori Toyofuku; Annelies S Zinkernagel; Leo Eberl; Carmen Menzi; Ratchara Kalawong; Srikanth Mairpady Shambat; Patrice François
Journal:  Antimicrob Agents Chemother       Date:  2019-01-29       Impact factor: 5.191

3.  The Staphylococcus aureus ArlRS two-component system regulates virulence factor expression through MgrA.

Authors:  Heidi A Crosby; Nitija Tiwari; Jakub M Kwiecinski; Zhen Xu; Allison Dykstra; Christian Jenul; Ernesto J Fuentes; Alexander R Horswill
Journal:  Mol Microbiol       Date:  2019-11-06       Impact factor: 3.501

4.  Staphylococcus aureus hyaluronidase is a CodY-regulated virulence factor.

Authors:  Carolyn B Ibberson; Crystal L Jones; Shweta Singh; Matthew C Wise; Mark E Hart; Daniel V Zurawski; Alexander R Horswill
Journal:  Infect Immun       Date:  2014-07-28       Impact factor: 3.441

5.  XerD unloads bacterial SMC complexes at the replication terminus.

Authors:  Xheni Karaboja; Zhongqing Ren; Hugo B Brandão; Payel Paul; David Z Rudner; Xindan Wang
Journal:  Mol Cell       Date:  2021-01-19       Impact factor: 17.970

6.  Alternating antibiotic treatments constrain evolutionary paths to multidrug resistance.

Authors:  Seungsoo Kim; Tami D Lieberman; Roy Kishony
Journal:  Proc Natl Acad Sci U S A       Date:  2014-09-22       Impact factor: 11.205

7.  Comprehensive Genome-wide Perturbations via CRISPR Adaptation Reveal Complex Genetics of Antibiotic Sensitivity.

Authors:  Wenyan Jiang; Panos Oikonomou; Saeed Tavazoie
Journal:  Cell       Date:  2020-02-27       Impact factor: 41.582

8.  Identification of Small Molecules Exhibiting Oxacillin Synergy through a Novel Assay for Inhibition of vraTSR Expression in Methicillin-Resistant Staphylococcus aureus.

Authors:  Hyun Lee; Susan Boyle-Vavra; Jinhong Ren; Jamie A Jarusiewicz; Lalit Kumar Sharma; Daniel T Hoagland; Shaohui Yin; Tian Zhu; Kirk E Hevener; Isabel Ojeda; Richard E Lee; Robert S Daum; Michael E Johnson
Journal:  Antimicrob Agents Chemother       Date:  2019-08-23       Impact factor: 5.191

9.  In Staphylococcus aureus, the Particulate State of the Cell Envelope Is Required for the Efficient Induction of Host Defense Responses.

Authors:  ByungHyun Kim; TingTing Jiang; Jun-Hyun Bae; Hye Su Yun; Seong Han Jang; Jung Hyun Kim; Jae Deog Kim; Jin-Hoe Hur; Kensuke Shibata; Kenji Kurokawa; Yunjin Jung; Andreas Peschel; Taeok Bae; Bok Luel Lee
Journal:  Infect Immun       Date:  2019-11-18       Impact factor: 3.441

10.  Evolution in fast forward: a potential role for mutators in accelerating Staphylococcus aureus pathoadaptation.

Authors:  Gregory S Canfield; Johanna M Schwingel; Matthew H Foley; Kelly L Vore; Kanitsak Boonanantanasarn; Ann L Gill; Mark D Sutton; Steven R Gill
Journal:  J Bacteriol       Date:  2012-11-30       Impact factor: 3.490
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