Literature DB >> 21378053

Construction and application of a functional library of cytochrome P450 monooxygenases from the filamentous fungus Aspergillus oryzae.

K H M Nazmul Hussain Nazir1, Hirofumi Ichinose, Hiroyuki Wariishi.   

Abstract

A functional library of cytochrome P450 monooxygenases from Aspergillus oryzae (AoCYPs) was constructed in which 121 isoforms were coexpressed with yeast NADPH-cytochrome P450 oxidoreductase in Saccharomyces cerevisiae. Using this functional library, novel catalytic functions of AoCYPs, such as catalytic potentials of CYP57B3 against genistein, were elucidated for the first time. Comprehensive functional screening promises rapid characterization of catalytic potentials and utility of AoCYPs.

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Year:  2011        PMID： 21378053      PMCID： PMC3126401          DOI： 10.1128/AEM.02491-10

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  39 in total

1.  Biodiversity of the P450 catalytic cycle: yeast cytochrome b5/NADH cytochrome b5 reductase complex efficiently drives the entire sterol 14-demethylation (CYP51) reaction.

Authors:  D C Lamb; D E Kelly; N J Manning; M A Kaderbhai; S L Kelly
Journal:  FEBS Lett       Date:  1999-12-03       Impact factor: 4.124

Review 2.  The natural functions of secondary metabolites.

Authors:  A L Demain; A Fang
Journal:  Adv Biochem Eng Biotechnol       Date:  2000       Impact factor: 2.635

3.  THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES.

Authors:  T OMURA; R SATO
Journal:  J Biol Chem       Date:  1964-07       Impact factor: 5.157

4.  Cytochrome P450 monooxygenases involved in anthracene metabolism by the white-rot basidiomycete Phanerochaete chrysosporium.

Authors:  Nomathemba Loice Chigu; Sinji Hirosue; Chie Nakamura; Hiroshi Teramoto; Hirofumi Ichinose; Hiroyuki Wariishi
Journal:  Appl Microbiol Biotechnol       Date:  2010-05-28       Impact factor: 4.813

Review 5.  Genistein.

Authors:  Richard A Dixon; Daneel Ferreira
Journal:  Phytochemistry       Date:  2002-06       Impact factor: 4.072

6.  Bioconversion of recalcitrant 4-methyldibenzothiophene to water-extractable products using lignin-degrading basidiomycete coriolus versicolor

Authors: 
Journal:  Biotechnol Prog       Date:  1999-07

7.  Engineering Escherichia coli for production of functionalized terpenoids using plant P450s.

Authors:  Michelle C Y Chang; Rachel A Eachus; William Trieu; Dae-Kyun Ro; Jay D Keasling
Journal:  Nat Chem Biol       Date:  2007-04-15       Impact factor: 15.040

8.  The cytochrome p450 homepage.

Authors:  David R Nelson
Journal:  Hum Genomics       Date:  2009-10       Impact factor: 4.639

Review 9.  Recombinant yeast in drug metabolism.

Authors:  J P Renaud; M A Peyronneau; P Urban; G Truan; C Cullin; D Pompon; P Beaune; D Mansuy
Journal:  Toxicology       Date:  1993-10-05       Impact factor: 4.221

Review 10.  The many roles of cytochrome b5.

Authors:  John B Schenkman; Ingela Jansson
Journal:  Pharmacol Ther       Date:  2003-02       Impact factor: 12.310
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  8 in total

1.  Structural insights into the mechanism of the drastic changes in enzymatic activity of the cytochrome P450 vitamin D3 hydroxylase (CYP107BR1) caused by a mutation distant from the active site.

Authors:  Yoshiaki Yasutake; Tomoshi Kameda; Tomohiro Tamura
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2017-04-26       Impact factor: 1.056

Review 2.  Versatile biocatalysis of fungal cytochrome P450 monooxygenases.

Authors:  Pradeepraj Durairaj; Jae-Seoun Hur; Hyungdon Yun
Journal:  Microb Cell Fact       Date:  2016-07-18       Impact factor: 5.328

Review 3.  Recombinant production of eukaryotic cytochrome P450s in microbial cell factories.

Authors:  Johanna Hausjell; Heidi Halbwirth; Oliver Spadiut
Journal:  Biosci Rep       Date:  2018-03-05       Impact factor: 3.840

4.  Migratory birds as the potential source for the transmission of Aspergillus and other fungus to Bangladesh.

Authors:  Mily Akter; Md Saiful Islam; Md Amirul Islam; Md Abdus Sobur; Md Salim Jahan; Saifur Rahman; K H M Nazmul Hussain Nazir; Md Tanvir Rahman
Journal:  J Adv Vet Anim Res       Date:  2020-05-07

5.  Altering the Regioselectivity of Cytochrome P450 BM3 Variant M13 toward Genistein through Protein Engineering and Variation of Reaction Conditions.

Authors:  Li-Li Hong; Jian-Qiang Kong
Journal:  ACS Omega       Date:  2020-12-02

6.  Evolution and enrichment of CYP5035 in Polyporales: functionality of an understudied P450 family.

Authors:  Nico D Fessner; David R Nelson; Anton Glieder
Journal:  Appl Microbiol Biotechnol       Date:  2021-08-30       Impact factor: 4.813

Review 7.  Isolation, bioactivity, and production of ortho-hydroxydaidzein and ortho-hydroxygenistein.

Authors:  Te-Sheng Chang
Journal:  Int J Mol Sci       Date:  2014-04-03       Impact factor: 5.923

8.  Insight into metabolic diversity of the brown-rot basidiomycete Postia placenta responsible for sesquiterpene biosynthesis: semi-comprehensive screening of cytochrome P450 monooxygenase involved in protoilludene metabolism.

Authors:  Hirofumi Ichinose; Takuya Kitaoka
Journal:  Microb Biotechnol       Date:  2018-08-13       Impact factor: 5.813
  8 in total

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