Literature DB >> 21378052

Isolation of a novel Aggregatibacter actinomycetemcomitans serotype b bacteriophage capable of lysing bacteria within a biofilm.

Mario Castillo-Ruiz1, Enrique D Vinés, Camilo Montt, Jorge Fernández, José Manuel Delgado, Juan Carlos Hormazábal, Mauricio Bittner.   

Abstract

A bacteriophage specific for Aggregatibacter actinomycetemcomitans serotype b, able to kill the bacterium within a biofilm, was isolated. Random mutagenesis of this phage rendered a bacteriophage able to kill 99% of the bacteria within a biofilm. This is the first report of a biocontrol experiment against A. actinomycetemcomitans.

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Year:  2011        PMID： 21378052      PMCID： PMC3126385          DOI： 10.1128/AEM.02115-10

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  26 in total

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