Literature DB >> 2137726

Methotrexate sensitivity in Down's syndrome: a hypothesis.

P M Ueland1, H Refsum, B Christensen.   

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Year:  1990        PMID： 2137726     DOI： 10.1007/bf00686245

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN： 0344-5704            Impact factor:   3.333


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  21 in total

1.  Leucocyte ultrastructure and folate metabolism in Down's syndrome.

Authors:  G S Gericke; P B Hesseling; S Brink; F C Tiedt
Journal:  S Afr Med J       Date:  1977-03-19

2.  Is absence of atheroma in Down syndrome due to decreased homocysteine levels?

Authors:  B Chadefaux; I Ceballos; M Hamet; M Coude; M Poissonnier; P Kamoun; D Allard
Journal:  Lancet       Date:  1988-09-24       Impact factor: 79.321

3.  The effect of methionine on methotrexate metabolism in rat hepatocytes in monolayer culture.

Authors:  M S Rhee; T B Johnson; D G Priest; J Galivan
Journal:  Biochim Biophys Acta       Date:  1989-05-10

4.  Cystathionine beta synthase: gene dosage effect in trisomy 21.

Authors:  B Chadefaux; M O Rethoré; O Raoul; I Ceballos; M Poissonnier; S Gilgenkranz; D Allard
Journal:  Biochem Biophys Res Commun       Date:  1985-04-16       Impact factor: 3.575

5.  Pharmacokinetics and toxicity of methotrexate in children with Down syndrome and acute lymphocytic leukemia.

Authors:  M L Garré; M V Relling; D Kalwinsky; R Dodge; W R Crom; M Abromowitch; C H Pui; W E Evans
Journal:  J Pediatr       Date:  1987-10       Impact factor: 4.406

6.  Mammalian folylpoly-gamma-glutamate synthetase. 2. Substrate specificity and kinetic properties.

Authors:  D J Cichowicz; B Shane
Journal:  Biochemistry       Date:  1987-01-27       Impact factor: 3.162

7.  The effect of methotrexate on intracellular folate pools in human MCF-7 breast cancer cells. Evidence for direct inhibition of purine synthesis.

Authors:  C J Allegra; R L Fine; J C Drake; B A Chabner
Journal:  J Biol Chem       Date:  1986-05-15       Impact factor: 5.157

8.  Demonstration, by somatic cell genetics, of coordinate regulation of genes for two enzymes of purine synthesis assigned to human chromosome 21.

Authors:  D Patterson; S Graw; C Jones
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

9.  Mechanisms of folate homeostasis.

Authors:  S E Steinberg
Journal:  Am J Physiol       Date:  1984-04

10.  Methotrexate hepatotoxicity.

Authors:  A J Barak; D J Tuma; H C Beckenhauer
Journal:  J Am Coll Nutr       Date:  1984       Impact factor: 3.169
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  8 in total

1.  Homocysteine and the methotrexate toxicity in trisomy 21.

Authors:  J Lejeune; M Peeters; M O Rethore; M C de Blois
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

2.  Transcriptional regulation of the human cystathionine beta-synthase -1b basal promoter: synergistic transactivation by transcription factors NF-Y and Sp1/Sp3.

Authors:  Y Ge; M A Konrad; L H Matherly; J W Taub
Journal:  Biochem J       Date:  2001-07-01       Impact factor: 3.857

3.  Homocysteine and related genetic polymorphisms in Down's syndrome IQ.

Authors:  J-L Guéant; G Anello; P Bosco; R-M Guéant-Rodríguez; A Romano; C Barone; P Gérard; C Romano
Journal:  J Neurol Neurosurg Psychiatry       Date:  2005-05       Impact factor: 10.154

4.  Homocysteine metabolism in children with Down syndrome: in vitro modulation.

Authors:  M Pogribna; S Melnyk; I Pogribny; A Chango; P Yi; S J James
Journal:  Am J Hum Genet       Date:  2001-06-05       Impact factor: 11.025

5.  Methotrexate-induced side effects are not due to differences in pharmacokinetics in children with Down syndrome and acute lymphoblastic leukemia.

Authors:  Trudy D Buitenkamp; Ron A A Mathôt; Valerie de Haas; Rob Pieters; C Michel Zwaan
Journal:  Haematologica       Date:  2010-04-23       Impact factor: 9.941

Review 6.  Modeling cellular compartmentation in one-carbon metabolism.

Authors:  Marco Scotti; Lorenzo Stella; Emily J Shearer; Patrick J Stover
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2013-02-13

7.  Association of methylenetetrahydrofolate reductase gene 677C > T polymorphism and Down syndrome.

Authors:  Marcelo Aguiar Costa-Lima; Márcia Rodrigues Amorim; Iêda Maria Orioli
Journal:  Mol Biol Rep       Date:  2012-11-25       Impact factor: 2.316

8.  One-carbon pathway and cognitive skills in children with Down syndrome.

Authors:  Francesca Antonaros; Silvia Lanfranchi; Chiara Locatelli; Anna Martelli; Giulia Olivucci; Elena Cicchini; Ludovica Carosi Diatricch; Elisa Mannini; Beatrice Vione; Agnese Feliciello; Giuseppe Ramacieri; Sara Onnivello; Renzo Vianello; Lorenza Vitale; Maria Chiara Pelleri; Pierluigi Strippoli; Guido Cocchi; Francesca Pulina; Allison Piovesan; Maria Caracausi
Journal:  Sci Rep       Date:  2021-02-19       Impact factor: 4.379
  8 in total

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