Literature DB >> 21372749

Successful management of chronic multifocal Q fever Osteomyelitis with adjuvant interferon-gamma therapy.

Olaf Werner Neth1, Dolores Falcon, Estrella Peromingo, Maria Soledad Camacho, Carlos Rodríguez-Gallego, Ignacio Obando.   

Abstract

We present a 3-year-old girl who had chronic recurrent multifocal osteomyelitis caused by Coxiella burnetii despite long-term dual antibiotic therapy. Excellent clinical response was achieved and sustained when immunomodulatory therapy with interferon-γ was initiated. This is the case of a first child who was successfully treated with interferon-γ as adjuvant therapy for chronic multifocal Q fever osteomyelitis.

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Year:  2011        PMID： 21372749     DOI： 10.1097/INF.0b013e31821487f5

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  7 in total

Review 1.  From Q Fever to Coxiella burnetii Infection: a Paradigm Change.

Authors:  Carole Eldin; Cléa Mélenotte; Oleg Mediannikov; Eric Ghigo; Matthieu Million; Sophie Edouard; Jean-Louis Mege; Max Maurin; Didier Raoult
Journal:  Clin Microbiol Rev       Date:  2017-01       Impact factor: 26.132

2.  Dysregulation of serum gamma interferon levels in vascular chronic Q Fever patients provides insights into disease pathogenesis.

Authors:  Jeroen L A Pennings; Marjolein N T Kremers; Hennie M Hodemaekers; Julia C J P Hagenaars; Olivier H J Koning; Nicole H M Renders; Mirjam H A Hermans; Arja de Klerk; Daan W Notermans; Peter C Wever; Riny Janssen
Journal:  Clin Vaccine Immunol       Date:  2015-04-29

3.  A case of Q fever prosthetic joint infection and description of an assay for detection of Coxiella burnetii.

Authors:  Aaron J Tande; Scott A Cunningham; Didier Raoult; Franklin H Sim; Elie F Berbari; Robin Patel
Journal:  J Clin Microbiol       Date:  2012-10-17       Impact factor: 5.948

4.  No differences of immune activation and microbial translocation among HIV-infected children receiving combined antiretroviral therapy or protease inhibitor monotherapy.

Authors:  Lola Falcon-Neyra; Omar J Benmarzouk-Hidalgo; Lola Madrid; Antoni Noguera-Julian; Claudia Fortuny; Olaf Neth; Luis López-Cortés
Journal:  Medicine (Baltimore)       Date:  2015-03       Impact factor: 1.889

5.  Reactivation of Q fever: case report of osteoarticular infection developing at the site of a soft tissue injury.

Authors:  Genevieve L McKew; Thomas Gottlieb
Journal:  Access Microbiol       Date:  2021-12-10

6.  Pediatric acute Q fever mimics other common childhood illnesses.

Authors:  Ingeborg Y Bart; Yvonne Schabos; Roeland W N M van Hout; Alexander C A P Leenders; Esther de Vries
Journal:  PLoS One       Date:  2014-02-10       Impact factor: 3.240

7.  Q Fever Osteoarticular Infection in Children.

Authors:  Halima Dabaja-Younis; Michal Meir; Anat Ilivizki; Daniela Militianu; Mark Eidelman; Imad Kassis; Yael Shachor-Meyouhas
Journal:  Emerg Infect Dis       Date:  2020-09       Impact factor: 6.883
  7 in total

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