Literature DB >> 2137273

Importance of DQB as an indicator in living-related kidney transplant.

N Matsuno1, H Inoko, A Ando, T Nakatsuji, T Sato, S Itchikawa, T Sonoda, K Tsuji.   

Abstract

Southern blot hybridization was performed in 16 pairs of living-related kidney transplant patients and donors, using DNA samples extracted from peripheral blood lymphocytes. The number of HLA-DNA-mismatched bands was used as an indicator for graft survival. The total number of DNA-mismatched bands seemed to be a valuable parameter. This was further analyzed and it was found that DQB in particular could be used to predict graft survival. Especially, usefulness of HLA-DNA typing was found in positive MLR, where good prognosis was strongly related to DQB matching. This method can therefore be applied in selecting a suitable living-related donor with the best chance of graft survival.

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Year:  1990        PMID： 2137273     DOI： 10.1097/00007890-199001000-00046

Source DB:  PubMed          Journal:  Transplantation        ISSN： 0041-1337            Impact factor:   4.939


  4 in total

1.  HLAMatchmaker: a molecularly based algorithm for histocompatibility determination. V. Eplet matching for HLA-DR, HLA-DQ, and HLA-DP.

Authors:  Rene J Duquesnoy; Medhat Askar
Journal:  Hum Immunol       Date:  2006-10-30       Impact factor: 2.850

2.  Retransplant candidates have donor-specific antibodies that react with structurally defined HLA-DR,DQ,DP epitopes.

Authors:  Rene J Duquesnoy; Yehia Awadalla; Jon Lomago; Larry Jelinek; Judy Howe; Dwayne Zern; Betty Hunter; Joan Martell; Alin Girnita; Adriana Zeevi
Journal:  Transpl Immunol       Date:  2007-10-30       Impact factor: 1.708

3.  An appraisal of pediatric liver transplantation from living relatives. Initial clinical experiences in 20 pediatric liver transplantations from living relatives as donors.

Authors:  K Ozawa; S Uemoto; K Tanaka; K Kumada; Y Yamaoka; N Kobayashi; T Inamoto; Y Shimahara; K Mori; K Honda
Journal:  Ann Surg       Date:  1992-11       Impact factor: 12.969

4.  Surgical techniques and innovations in living related liver transplantation.

Authors:  K Tanaka; S Uemoto; Y Tokunaga; S Fujita; K Sano; T Nishizawa; H Sawada; I Shirahase; H J Kim; Y Yamaoka
Journal:  Ann Surg       Date:  1993-01       Impact factor: 12.969
  4 in total

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