Literature DB >> 21371337

An immunocompetent adult patient with hepatitis and guillain-barré syndrome after cytomegalovirus infection.

Ying Ma1, Juan Feng, Ying Qi, Xiao Guang Dou.   

Abstract

OBJECTIVES: It is to describe an immunocompetent adult patient with hepatitis and Guillain-Barré syndrome (GBS) after Cytomegalovirus (CMV) infection. In the initial course of the diagnosis and treatment, CMV infection was ignored. CASE REPORT: A 19-year-old Chinese girl complained of fatigue with pain and numbness of the limbs, with abnormal liver function. She was diagnosed as a case of GBS based on history, clinical findings and auxiliary examinations. On day 13 of admission, her liver function was still abnormal. So CMV was recommended to examine. CMV hepatitis was diagnosed on positive serum anti-CMV IgG and IgM antibodies. The case was improved only with intravenous immunoglobulin therapy, without the use of antiviral therapy.
CONCLUSIONS: This case showed an immunocompetent adult patient with hepatitis and GBS induced by CMV. The physicians should take into account multi-system involvement of severe CMV infection.

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Year:  2011        PMID: 21371337      PMCID: PMC3059287          DOI: 10.1186/1743-422X-8-95

Source DB:  PubMed          Journal:  Virol J        ISSN: 1743-422X            Impact factor:   4.099


  12 in total

1.  Cytomegalovirus meningoencephalitis with paroxysmal course in immunocompetent adults: a new nosographical entity. Clinical, diagnostic and therapeutic correlations, and pathogenetic hypothesis.

Authors:  F C Devetag; L Boscariolo
Journal:  Eur Neurol       Date:  2000       Impact factor: 1.710

2.  A randomized trial comparing intravenous immune globulin and plasma exchange in Guillain-Barré syndrome. Dutch Guillain-Barré Study Group.

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Journal:  N Engl J Med       Date:  1992-04-23       Impact factor: 91.245

3.  An adolescent with pharyngeal-cervical-brachial variant of Guillain-Barré syndrome after cytomegalovirus infection.

Authors:  Nobuyuki Murakami; Yuzo Tomita; Michiaki Koga; Etsuro Takahashi; Yasuki Katada; Ryoichi Sakuta; Toshiro Nagai
Journal:  Brain Dev       Date:  2005-12-20       Impact factor: 1.961

Review 4.  Assessment of current diagnostic criteria for Guillain-Barré syndrome.

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Journal:  Ann Neurol       Date:  1990       Impact factor: 10.422

Review 5.  Cytomegalovirus infection in immunocompetent and immunocompromised individuals--a review.

Authors:  Z Vancíková; P Dvorák
Journal:  Curr Drug Targets Immune Endocr Metabol Disord       Date:  2001-08

Review 6.  Guillain-Barré syndrome.

Authors:  Richard A C Hughes; David R Cornblath
Journal:  Lancet       Date:  2005-11-05       Impact factor: 79.321

7.  Cytomegalovirus infection in the normal host.

Authors:  J I Cohen; G R Corey
Journal:  Medicine (Baltimore)       Date:  1985-03       Impact factor: 1.889

Review 8.  [Severe CMV infection: not only in immunocompromised patients].

Authors:  O Giroud; P Meier; D San Millán; G Praz
Journal:  Rev Med Suisse       Date:  2010-10-13

9.  Cytomegalovirus induced hepatitis in an immunocompetent host.

Authors:  A K Azad; T Ahmed; A J Chowdhury; M A Rahim; A K Mahmud; M A Rahman
Journal:  Mymensingh Med J       Date:  2008-07

Review 10.  Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review.

Authors:  Petros I Rafailidis; Eleni G Mourtzoukou; Ioannis C Varbobitis; Matthew E Falagas
Journal:  Virol J       Date:  2008-03-27       Impact factor: 4.099

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  3 in total

1.  Cytomegalovirus hepatitis and pancreatitis in the immunocompetent.

Authors:  Aaron Chan; Fateh Bazerbachi; Brian Hanson; M Chadi Alraies; Alisa Duran-Nelson
Journal:  Ochsner J       Date:  2014

2.  Acute cytomegalovirus hepatitis in an immunocompetent host.

Authors:  Alexander M Sy; Olabimpe Omobomi; Theodore Lenox; Nora V Bergasa
Journal:  BMJ Case Rep       Date:  2013-11-25

Review 3.  Cytomegalovirus Hepatitis in Immunocompetent and Immunocompromised Hosts.

Authors:  Teresa Da Cunha; George Y Wu
Journal:  J Clin Transl Hepatol       Date:  2021-01-04
  3 in total

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