Literature DB >> 2137073

Factor H.

D P Vik1, P Muñoz-Cánoves, D D Chaplin, B F Tack.   

Abstract

While the mouse and human H proteins are structurally and functionally similar, they differ in their genetics. Whereas there is no evidence in humans for more than one gene; in mice the H locus is complex. Based on cDNA sequence and hybridization analysis of genomic cosmid clones, there are at least three distinct genes, all highly related to one another. The consensus repeating unit that comprises this molecule has obviously been duplicated numerous times, since it is present in many other molecules. Thus, it is not surprising to discover that there are several genes related to H in the mouse. A similar case has been described for two other members of this family. In humans, CR1 cDNA hybridizes to two distinct genomic clusters in the CR1 locus (Wong et al. 1989), and in mice, mCRY hybridizes to two regions in the genome, one on chromosome 1 and another on chromosome 8 (Aegerter-Shaw et al. 1987). It will be of interest to see if any other members of this family display as complex a genetic locus as murine H.

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Year:  1990        PMID: 2137073     DOI: 10.1007/978-3-642-74977-3_8

Source DB:  PubMed          Journal:  Curr Top Microbiol Immunol        ISSN: 0070-217X            Impact factor:   4.291


  11 in total

Review 1.  Target recognition failure by the nonspecific defense system: surface constituents of pathogens interfere with the alternative pathway of complement activation.

Authors:  R D Horstmann
Journal:  Infect Immun       Date:  1992-03       Impact factor: 3.441

Review 2.  Complement control protein factor H: the good, the bad, and the inadequate.

Authors:  Viviana P Ferreira; Michael K Pangburn; Claudio Cortés
Journal:  Mol Immunol       Date:  2010-08       Impact factor: 4.407

3.  Effect of complement-protein-C3b density on the binding of complement factor H to surface-bound C3b.

Authors:  V Koistinen
Journal:  Biochem J       Date:  1991-11-15       Impact factor: 3.857

4.  Acquisition of factor H by a novel surface protein on group B Streptococcus promotes complement degradation.

Authors:  Ravi Maruvada; Nemani V Prasadarao; C E Rubens
Journal:  FASEB J       Date:  2009-07-16       Impact factor: 5.191

5.  The C-terminus of factor H: monoclonal antibodies inhibit heparin binding and identify epitopes common to factor H and factor H-related proteins.

Authors:  W M Prodinger; J Hellwage; M Spruth; M P Dierich; P F Zipfel
Journal:  Biochem J       Date:  1998-04-01       Impact factor: 3.857

6.  Inherited factor H deficiency and collagen type III glomerulopathy.

Authors:  B A Vogt; R J Wyatt; B A Burke; S C Simonton; C E Kashtan
Journal:  Pediatr Nephrol       Date:  1995-02       Impact factor: 3.714

7.  Contribution of the infection-associated complement regulator-acquiring surface protein 4 (ErpC) to complement resistance of Borrelia burgdorferi.

Authors:  Claudia Hammerschmidt; Teresia Hallström; Christine Skerka; Reinhard Wallich; Brian Stevenson; Peter F Zipfel; Peter Kraiczy
Journal:  Clin Dev Immunol       Date:  2012-01-30

8.  C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an antiinflammatory innate immune response: implications for systemic autoimmunity.

Authors:  D Gershov; S Kim; N Brot; K B Elkon
Journal:  J Exp Med       Date:  2000-11-06       Impact factor: 14.307

9.  ErpC, a member of the complement regulator-acquiring family of surface proteins from Borrelia burgdorferi, possesses an architecture previously unseen in this protein family.

Authors:  Joseph J E Caesar; Steven Johnson; Peter Kraiczy; Susan M Lea
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2013-05-23

10.  Further structural insights into the binding of complement factor H by complement regulator-acquiring surface protein 1 (CspA) of Borrelia burgdorferi.

Authors:  Joseph J E Caesar; Reinhard Wallich; Peter Kraiczy; Peter F Zipfel; Susan M Lea
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2013-05-23
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