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Literature DB >> 21370372

Total synthesis of pactamycin.

Stephen Hanessian¹, Ramkrishna Reddy Vakiti, Stéphane Dorich, Shyamapada Banerjee, Fabien Lecomte, Juan R DelValle, Jianbin Zhang, Benoît Deschênes-Simard.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2011 PMID： 21370372 DOI： 10.1002/anie.201008079

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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16 in total

Review 1. Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.

Authors: K C Nicolaou; Christopher R H Hale; Christian Nilewski; Heraklidia A Ioannidou
Journal: Chem Soc Rev Date: 2012-06-28 Impact factor: 54.564

2. Stereocontrolled Synthesis of the Aminocyclopentitol Core of Jogyamycin via an Ichikawa Rearrangement Reaction.

Authors: Nels C Gerstner; Jennifer M Schomaker
Journal: J Org Chem Date: 2019-10-16 Impact factor: 4.354

3. Diastereocontrolled construction of pactamycin's complex ureido triol functional array.

Authors: Justin T Malinowski; Stefan J McCarver; Jeffrey S Johnson
Journal: Org Lett Date: 2012-05-22 Impact factor: 6.005

4. Preparation and biological evaluation of synthetic and polymer-encapsulated congeners of the antitumor agent pactamycin: insight into functional group effects and biological activity.

Authors: Robert J Sharpe; Justin T Malinowski; Federico Sorana; J Christopher Luft; Charles J Bowerman; Joseph M DeSimone; Jeffrey S Johnson
Journal: Bioorg Med Chem Date: 2015-02-21 Impact factor: 3.641

Total synthesis of pactamycin.

Review 1. Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.

2. Stereocontrolled Synthesis of the Aminocyclopentitol Core of Jogyamycin via an Ichikawa Rearrangement Reaction.

3. Diastereocontrolled construction of pactamycin's complex ureido triol functional array.

4. Preparation and biological evaluation of synthetic and polymer-encapsulated congeners of the antitumor agent pactamycin: insight into functional group effects and biological activity.

5. Enantioselective synthesis of pactamycin, a complex antitumor antibiotic.

6. Mutasynthesis of fluorinated pactamycin analogues and their antimalarial activity.

7. Methods for direct alkene diamination, new & old.

8. Diastereoselective Synthesis of the Aminocyclitol Core of Jogyamycin via an Allene Aziridination Strategy.

Review 9. Strategies for the Syntheses of Pactamycin and Jogyamycin.

10. Asymmetric synthesis of the aminocyclitol pactamycin, a universal translocation inhibitor.