Literature DB >> 21370347

Selective treatment of hypoxic tumor cells in vivo: phosphate pre-prodrugs of nitro analogues of the duocarmycins.

Moana Tercel1, Graham J Atwell, Shangjin Yang, Amir Ashoorzadeh, Ralph J Stevenson, K Jane Botting, Yongchuan Gu, Sunali Y Mehta, William A Denny, William R Wilson, Frederik B Pruijn.   

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Year:  2011        PMID： 21370347     DOI： 10.1002/anie.201004456

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  9 in total

1.  A five-membered lactone prodrug of CBI-based analogs of the duocarmycins.

Authors:  Mika Uematsu; Daniel M Brody; Dale L Boger
Journal:  Tetrahedron Lett       Date:  2015-06-03       Impact factor: 2.415

Review 2.  Targeting hypoxia in cancer therapy.

Authors:  William R Wilson; Michael P Hay
Journal:  Nat Rev Cancer       Date:  2011-06       Impact factor: 60.716

3.  Efficacious cyclic N-acyl O-amino phenol duocarmycin prodrugs.

Authors:  Amanda L Wolfe; Katharine K Duncan; Nikhil K Parelkar; Douglas Brown; George A Vielhauer; Dale L Boger
Journal:  J Med Chem       Date:  2013-05-10       Impact factor: 7.446

4.  A novel, unusually efficacious duocarmycin carbamate prodrug that releases no residual byproduct.

Authors:  Amanda L Wolfe; Katharine K Duncan; Nikhil K Parelkar; Scott J Weir; George A Vielhauer; Dale L Boger
Journal:  J Med Chem       Date:  2012-06-12       Impact factor: 7.446

5.  Radioactive phosphorylation of alcohols to monitor biocatalytic Diels-Alder reactions.

Authors:  Alexander Nierth; Andres Jäschke
Journal:  PLoS One       Date:  2011-06-22       Impact factor: 3.240

6.  Impact of Tumour Hypoxia on Evofosfamide Sensitivity in Head and Neck Squamous Cell Carcinoma Patient-Derived Xenograft Models.

Authors:  Julia K Harms; Tet-Woo Lee; Tao Wang; Amy Lai; Dennis Kee; John M Chaplin; Nick P McIvor; Francis W Hunter; Andrew M J Macann; William R Wilson; Stephen M F Jamieson
Journal:  Cells       Date:  2019-07-13       Impact factor: 6.600

Review 7.  Nitroaromatic Hypoxia-Activated Prodrugs for Cancer Therapy.

Authors:  William A Denny
Journal:  Pharmaceuticals (Basel)       Date:  2022-02-02

8.  Pseudomonas aeruginosa NfsB and nitro-CBI-DEI--a promising enzyme/prodrug combination for gene directed enzyme prodrug therapy.

Authors:  Laura K Green; Sophie P Syddall; Kendall M Carlin; Glenn D Bell; Christopher P Guise; Alexandra M Mowday; Michael P Hay; Jeffrey B Smaill; Adam V Patterson; David F Ackerley
Journal:  Mol Cancer       Date:  2013-06-10       Impact factor: 27.401

9.  Tumor reoxygenation for enhanced combination of radiation therapy and microwave thermal therapy using oxygen generation in situ by CuO nanosuperparticles under microwave irradiation.

Authors:  Zengzhen Chen; Wenna Guo; Qiong Wu; Longfei Tan; Tengchuang Ma; Changhui Fu; Jie Yu; Xiangling Ren; Jianming Wang; Ping Liang; Xianwei Meng
Journal:  Theranostics       Date:  2020-03-25       Impact factor: 11.556
  9 in total

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