Literature DB >> 21369708

Macrophages and neutrophils cooperate in immune responses to Leishmania infection.

Alessandra A Filardy1, Dayana R Pires, George A DosReis.   

Abstract

Neutrophils and macrophages are phagocytic cells that cooperate during inflammation and tissue repair. Neutrophils undergo apoptosis and are engulfed by macrophages. Engulfment modulates macrophage activation and microbicidal activity. Infection by Leishmania takes place in the context of tissue repair. This article discusses cellular and molecular mechanisms involved in the intimate cooperation of neutrophils and macrophages in Leishmania infection.

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Year:  2011        PMID: 21369708     DOI: 10.1007/s00018-011-0653-2

Source DB:  PubMed          Journal:  Cell Mol Life Sci        ISSN: 1420-682X            Impact factor:   9.261


  67 in total

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