Literature DB >> 21369503

Effect of Glucose Control on Delayed Gastric Emptying in Diabetic Patients: Author's Reply.

Carlos Palacio1, Kenneth J Vega.   

Abstract

Entities:  

Year:  2011        PMID: 21369503      PMCID: PMC3042212          DOI: 10.5056/jnm.2011.17.1.101

Source DB:  PubMed          Journal:  J Neurogastroenterol Motil        ISSN: 2093-0879            Impact factor:   4.924


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TO THE EDITOR: We thank Dr. Kim for her interest in our paper.1 We agree regarding the issues raised in the correspondence to the editor. The study under discussion was a retrospective analysis of an available serum hemoglobin A1C (HbA1C) level near the performance of a gastric emptying scan. As a result of this limitation, assessment of preprandial or postprandial glucose values as well as duration of diabetes and presence of diabetic complications could not be performed.2-5 Categorical analysis of our study patients with abnormal HbA1C (defined as greater than or equal to 7%) and abnormal gastric emptying times (defined as greater than or equal to 120 minutes) showed no statistically significant association (P = 0.525). Because analyses using gastric emptying time and HbA1C as continuous variables did not show conclusive differences, categorical analysis was not performed using cut-off times of 90 or 180 minutes. Further studies prospectively evaluating pre and postprandial glycemia, prolonged gylcemic control measured by multiple serum HbA1C levels over time, age and duration of diabetes diagnosis as well as presence of diabetic complications can further elucidate the relationship of these variables with one another and their effects on gastric emptying time.
  5 in total

Review 1.  Clinical practice. Diabetic gastroparesis.

Authors:  Michael Camilleri
Journal:  N Engl J Med       Date:  2007-02-22       Impact factor: 91.245

Review 2.  Pathophysiology and management of diabetic gastropathy: a guide for endocrinologists.

Authors:  Paul Kuo; Christopher K Rayner; Karen L Jones; Michael Horowitz
Journal:  Drugs       Date:  2007       Impact factor: 9.546

3.  Post-prandial hyperglycemia is an important predictor of the incidence of diabetic microangiopathy in Japanese type 2 diabetic patients.

Authors:  Toshihiko Shiraiwa; Hideaki Kaneto; Takeshi Miyatsuka; Ken Kato; Kaoru Yamamoto; Ayaha Kawashima; Tsutomu Kanda; Masaaki Suzuki; Eiichi Imano; Munehide Matsuhisa; Masatsugu Hori; Yoshimitsu Yamasaki
Journal:  Biochem Biophys Res Commun       Date:  2005-10-14       Impact factor: 3.575

Review 4.  Gastrointestinal motility and glycemic control in diabetes: the chicken and the egg revisited?

Authors:  Christopher K Rayner; Michael Horowitz
Journal:  J Clin Invest       Date:  2006-02       Impact factor: 14.808

5.  Do HbA1C Levels Correlate With Delayed Gastric Emptying in Diabetic Patients?

Authors:  Shilpa Reddy; Karishma Ramsubeik; Kenneth J Vega; Justin Federico; Carlos Palacio
Journal:  J Neurogastroenterol Motil       Date:  2010-10-30       Impact factor: 4.924

  5 in total

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