| Literature DB >> 21366341 |
Yan Wu1, Shan-Bin Qi, Fei-Fei Wu, Xi-Chang Zhang, Min Li, Jing Wu, Albert S C Chan.
Abstract
A new set of reaction conditions has been established to facilitate the copper-catalyzed enantioselective 1,4-reduction of β-(acylamino)acrylates toward a selection of β-alkyl-β-amino acid derivatives in high yields and with uniformly high ee values (up to 99%) irrespective of the use of (E)- or (Z)-substrates.Entities:
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Year: 2011 PMID： 21366341 DOI： 10.1021/ol200287z
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005