Literature DB >> 21365767

Structure-based repurposing of FDA-approved drugs as TNF-α inhibitors.

Chung-Hang Leung1, Daniel Shiu-Hin Chan, Maria Hiu-Tung Kwan, Zhen Cheng, Chun-Yuen Wong, Guo-Yuan Zhu, Wang-Fun Fong, Dik-Lung Ma.   

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Year:  2011        PMID： 21365767     DOI： 10.1002/cmdc.201100016

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  11 in total

1.  FDA approved drugs complexed to their targets: evaluating pose prediction accuracy of docking protocols.

Authors:  Mohammed H Bohari; G Narahari Sastry
Journal:  J Mol Model       Date:  2012-05-08       Impact factor: 1.810

2.  Screening bicyclic peptide libraries for protein-protein interaction inhibitors: discovery of a tumor necrosis factor-α antagonist.

Authors:  Wenlong Lian; Punit Upadhyaya; Curran A Rhodes; Yusen Liu; Dehua Pei
Journal:  J Am Chem Soc       Date:  2013-08-01       Impact factor: 15.419

3.  Hit identification of IKKβ natural product inhibitor.

Authors:  Chung-Hang Leung; Daniel Shiu-Hin Chan; Ying-Wei Li; Wang-Fun Fong; Dik-Lung Ma
Journal:  BMC Pharmacol Toxicol       Date:  2013-01-07       Impact factor: 2.483

4.  A novel coumarin, (+)-3'-angeloxyloxy-4'-keto-3',4'-dihydroseselin, isolated from Bupleurum malconense (Chaihu) inhibited NF-κB activity.

Authors:  Huai-Xue Mu; Cheng-Yuan Lin; Lin-Fang Huang; Da-Jian Yang; Ai-Ping Lu; Quan-Bin Han; Zhao-Xiang Bian
Journal:  Chin Med       Date:  2016-02-13       Impact factor: 5.455

5.  Thiopurine Drugs Repositioned as Tyrosinase Inhibitors.

Authors:  Joonhyeok Choi; You-Mie Lee; Jun-Goo Jee
Journal:  Int J Mol Sci       Date:  2017-12-28       Impact factor: 5.923

6.  Identification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screening.

Authors:  Hadley Mouhsine; Hélène Guillemain; Gabriel Moreau; Najla Fourati; Chouki Zerrouki; Bruno Baron; Lucille Desallais; Patrick Gizzi; Nesrine Ben Nasr; Julie Perrier; Rojo Ratsimandresy; Jean-Louis Spadoni; Hervé Do; Patrick England; Matthieu Montes; Jean-François Zagury
Journal:  Sci Rep       Date:  2017-06-13       Impact factor: 4.379

7.  Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).

Authors:  Georgia Melagraki; Evangelos Ntougkos; Vagelis Rinotas; Christos Papaneophytou; Georgios Leonis; Thomas Mavromoustakos; George Kontopidis; Eleni Douni; Antreas Afantitis; George Kollias
Journal:  PLoS Comput Biol       Date:  2017-04-20       Impact factor: 4.475

8.  Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors.

Authors:  Xiaobing Deng; Xiaoling Zhang; Bo Tang; Hongbo Liu; Qi Shen; Ying Liu; Luhua Lai
Journal:  Front Chem       Date:  2018-04-04       Impact factor: 5.221

9.  In Silico Discovery of Plant-Origin Natural Product Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).

Authors:  Georgia Melagraki; Evangelos Ntougkos; Dimitra Papadopoulou; Vagelis Rinotas; Georgios Leonis; Eleni Douni; Antreas Afantitis; George Kollias
Journal:  Front Pharmacol       Date:  2018-07-25       Impact factor: 5.810

10.  Aurone derivatives as Vps34 inhibitors that modulate autophagy.

Authors:  Guodong Li; Joshua William Boyle; Chung-Nga Ko; Wu Zeng; Vincent Kam Wai Wong; Jian-Bo Wan; Philip Wai Hong Chan; Dik-Lung Ma; Chung-Hang Leung
Journal:  Acta Pharm Sin B       Date:  2019-01-30       Impact factor: 11.413
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