Literature DB >> 21360103

The economic burden of rheumatoid arthritis: beyond health care costs.

Wei Zhang1, Aslam H Anis.   

Abstract

Rheumatoid arthritis (RA) not only causes significant morbidity, but also leads to substantial losses in terms of productivity that have a negative impact on the individual and the society. In countries, such as Canada, the US, and the UK, it is known that the costs to the economy in terms of sick leave and work-related disability run into billions of dollars. However, putting an accurate figure on these losses is not entirely straightforward. Most health-related studies use the "human capital" approach, which treats human beings as assets. A figure for lost productivity is calculated by multiplying hours lost by the hourly wage rate. It is a method that is not without its critics because of its emphasis on earning power, which discriminates against non-earners. Another method is the "friction-cost" approach, whereby absenteeism is only recorded if the missed work requires extra hours undertaken, either by the employee himself, or by the others. A third method is the "willingness-to-pay" approach which values life according to an individual's preference to avoid illness with an imputed monetary valuation on the various health outcomes being considered. A number of studies have shown that biologic RA treatments provide productivity benefits in terms of maintaining employment, as well as reducing absenteeism and presenteeism. Going forward, an approach recently adopted by the present authors with encouraging preliminary results, the Valuation of Lost Productivity, takes into account a wide range of factors to provide a measure of productivity that is as accurate as possible.

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Year:  2011        PMID: 21360103     DOI: 10.1007/s10067-010-1637-6

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN: 0770-3198            Impact factor:   2.980


  38 in total

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2.  The friction cost method for measuring indirect costs of disease.

Authors:  M A Koopmanschap; F F Rutten; B M van Ineveld; L van Roijen
Journal:  J Health Econ       Date:  1995-06       Impact factor: 3.883

3.  The willingness to pay for health changes, the human-capital approach and the external costs.

Authors:  M Johannesson
Journal:  Health Policy       Date:  1996-06       Impact factor: 2.980

4.  Work productivity among employed Canadians with arthritis.

Authors:  Wei Zhang; Mieke Koehoorn; Aslam H Anis
Journal:  J Occup Environ Med       Date:  2010-09       Impact factor: 2.162

5.  Productivity loss due to presenteeism among patients with arthritis: estimates from 4 instruments.

Authors:  Wei Zhang; Monique A M Gignac; Dorcas Beaton; Kenneth Tang; Aslam H Anis
Journal:  J Rheumatol       Date:  2010-07-01       Impact factor: 4.666

6.  Indirect and nonmedical costs among people with rheumatoid arthritis and osteoarthritis compared with nonarthritic controls.

Authors:  S E Gabriel; C S Crowson; M E Campion; W M O'Fallon
Journal:  J Rheumatol       Date:  1997-01       Impact factor: 4.666

7.  Short-term influence of adalimumab on work productivity outcomes in patients with rheumatoid arthritis.

Authors:  Wei Zhang; Nick Bansback; Daphne Guh; Xin Li; Bohdan Nosyk; Carlo A Marra; Aslam H Anis
Journal:  J Rheumatol       Date:  2008-08-01       Impact factor: 4.666

8.  Patients with rheumatoid arthritis treated with tumour necrosis factor antagonists increase their participation in the workforce: potential for significant long-term indirect cost gains (data from a population-based registry).

Authors:  J Augustsson; M Neovius; C Cullinane-Carli; S Eksborg; R F van Vollenhoven
Journal:  Ann Rheum Dis       Date:  2010-01       Impact factor: 19.103

9.  Worker productivity outcome measures in arthritis.

Authors:  Reuben Escorpizo; Claire Bombardier; Annelies Boonen; Johanna M W Hazes; Diane Lacaille; Vibeke Strand; Dorcas Beaton
Journal:  J Rheumatol       Date:  2007-06       Impact factor: 4.666

10.  Association between etanercept use and employment outcomes among patients with rheumatoid arthritis.

Authors:  Edward Yelin; Laura Trupin; Patricia Katz; Deborah Lubeck; Stephanie Rush; Lee Wanke
Journal:  Arthritis Rheum       Date:  2003-11
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  18 in total

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Journal:  Rheumatol Int       Date:  2014-02-09       Impact factor: 2.631

2.  Structural optimization of HPMA copolymer-based dexamethasone prodrug for improved treatment of inflammatory arthritis.

Authors:  Zhenshan Jia; Gang Zhao; Xin Wei; Dexuan Kong; Yuanyuan Sun; You Zhou; Subodh M Lele; Edward V Fehringer; Kevin L Garvin; Steven R Goldring; Dong Wang
Journal:  J Control Release       Date:  2020-05-20       Impact factor: 9.776

3.  Targeting interleukin-17 in patients with active rheumatoid arthritis: rationale and clinical potential.

Authors:  Herbert Kellner
Journal:  Ther Adv Musculoskelet Dis       Date:  2013-06       Impact factor: 5.346

4.  Productivity at work and quality of life in patients with rheumatoid arthritis.

Authors:  Myrthe van Vilsteren; Cecile R L Boot; Dirk L Knol; Dirkjan van Schaardenburg; Alexandre E Voskuyl; Romy Steenbeek; Johannes R Anema
Journal:  BMC Musculoskelet Disord       Date:  2015-05-06       Impact factor: 2.362

5.  Treating to the target of remission in early rheumatoid arthritis is cost-effective: results of the DREAM registry.

Authors:  Marloes Vermeer; Wietske Kievit; Hillechiena H Kuper; Louise M A Braakman-Jansen; Hein J Bernelot Moens; Theo R Zijlstra; Alfons A den Broeder; Piet L C M van Riel; Jaap Fransen; Mart A F J van de Laar
Journal:  BMC Musculoskelet Disord       Date:  2013-12-13       Impact factor: 2.362

6.  How much of the productivity losses among psoriasis patients are due to psoriasis.

Authors:  Anssi Mustonen; Kalle Mattila; Mauri Leino; Leena Koulu; Risto Tuominen
Journal:  BMC Health Serv Res       Date:  2015-03-04       Impact factor: 2.655

7.  Evolution of cost structures in rheumatoid arthritis over the past decade.

Authors:  Dörte Huscher; Thomas Mittendorf; Ulrich von Hinüber; Ina Kötter; Guido Hoese; Andrea Pfäfflin; Sascha Bischoff; Angela Zink
Journal:  Ann Rheum Dis       Date:  2014-01-09       Impact factor: 19.103

8.  Co-Occurrence of Arthritis and Stroke amongst Middle-Aged and Older Adults in Canada.

Authors:  Roman Matveev; Chris I Ardern
Journal:  Stroke Res Treat       Date:  2014-04-16

9.  Improvements in productivity at paid work and within the household, and increased participation in daily activities after 24 weeks of certolizumab pegol treatment of patients with psoriatic arthritis: results of a phase 3 double-blind randomised placebo-controlled study.

Authors:  A Kavanaugh; D Gladman; D van der Heijde; O Purcaru; P Mease
Journal:  Ann Rheum Dis       Date:  2014-06-18       Impact factor: 19.103

10.  Discordance between patient and physician assessments of global disease activity in rheumatoid arthritis and association with work productivity.

Authors:  Josef S Smolen; Vibeke Strand; Andrew S Koenig; Annette Szumski; Sameer Kotak; Thomas V Jones
Journal:  Arthritis Res Ther       Date:  2016-05-21       Impact factor: 5.156

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