Automatic inference of articulated spine models in CT images using high-order Markov Random Fields.

In this paper, we introduce a novel and efficient approach for inferring articulated 3D spine models from operative images. The problem is formulated as a Markov Random Field which has the ability to encode global structural dependencies to align CT volume images. A personalized geometrical model is first reconstructed from preoperative images before surgery, and subsequently decomposed as a series of intervertebral transformations based on rotation and translation parameters. The shape transformation between the standing and lying poses is achieved by optimizing the deformations applied to the intervertebral transformations. Singleton and pairwise potentials measure the support from the data and geometrical dependencies between neighboring vertebrae respectively, while higher-order cliques (groups of vertebrae) are introduced to integrate consistency in regional curves. Local vertebra modifications are achieved through a constrained mesh relaxation technique. Optimization of model parameters in a multimodal context is achieved using efficient linear programming and duality. Experimental and clinical evaluation of the vertebra model alignment obtained from the proposed method gave promising results. Quantitative comparison to expert identification yields an accuracy of 1.8±0.7mm based on the localization of surgical landmarks.