Literature DB >> 21352705

[Management of early rectal cancer: our clinical experience].

A Biondi1, A Tropea, G Monaco, N Musumeci, G Benfatto, F Basile.   

Abstract

AIM: Patients with early rectal cancer (ERC) limited to the mucosa and submucosa does not present cytological or histological high risk features such as poorly differentiated cells, vascular and neural invasion, presence of mucinous histology and tumor ulceration. In these patients, local excision of rectal tumors preserves anal continence, bladder and sexual functions and achieves the same oncological results. In T1 patients, local excision is feasible because the curative rate is high (90/95%) and the risk of recurrence that is low ( 5/10%) as reported in the literature. Aim of this study is to carry out the best clinical choice in patients ERC affected. We have examined patologic, laboratory exams and surgical technique performed. PATIENTS AND METHODS: From January 2004 to July 2009, 16 patients with rectal cancer were studied at the General Surgery and Oncology Department of Catania University. The middle size of the cancers at the implantation site were 3,4 cm (range: 3-5). The average distance from the anus were 5,8 cm (range: 4,5-10). The cancers were presented vegetanting and movable on the muscle surfaces below.
RESULTS: Istological exams pointed out pT1 neoplasia confined in submucosa in 13 patients, and in 3 patients pT2 neoplasia with a muscularis mucosae involvement. Istological grading found out G1 neoplasia in 9 cases and G2 in 7. Discussion. Low rectal cancers diagnosed in T1 stage necessitate an accurate preoperatory staging. Local exeresis can be a real alternative to traditional surgery. In these patients neoplasia exeresis can assure 5 years more survival in 85% of patients.
CONCLUSION: Local exeresis is a validate surgical way but is however necessary that istological exam confirms surgical oncology criteria. Must be confirmed that neoplasia is T1 with 1mm resection margin at least,differentiation G1-G2 and no venous or lymphatic infiltrations.

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Year:  2011        PMID: 21352705

Source DB:  PubMed          Journal:  G Chir        ISSN: 0391-9005


  4 in total

1.  Laparoscopic-assisted versus open surgery for colorectal cancer: short- and long-term outcomes comparison.

Authors:  Antonio Biondi; Giuseppe Grosso; Antonio Mistretta; Stefano Marventano; Chiara Toscano; Salvatore Gruttadauria; Francesco Basile
Journal:  J Laparoendosc Adv Surg Tech A       Date:  2012-09-24       Impact factor: 1.878

2.  Major postoperative complications and survival for colon cancer elderly patients.

Authors:  Giuseppe Grosso; Antonio Biondi; Stefano Marventano; Antonio Mistretta; Giorgio Calabrese; Francesco Basile
Journal:  BMC Surg       Date:  2012-11-15       Impact factor: 2.102

Review 3.  Pharmacological and dietary prevention for colorectal cancer.

Authors:  Francesca Nolfo; Stefania Rametta; Stefano Marventano; Giuseppe Grosso; Antonio Mistretta; Filippo Drago; Santi Gangi; Francesco Basile; Antonio Biondi
Journal:  BMC Surg       Date:  2013-10-08       Impact factor: 2.102

4.  Comparison of the clinical outcomes of laparoscopic-assisted versus open surgery for colorectal cancer.

Authors:  Kai Chen; Zhuqing Zhang; Yunfei Zuo; Shuangyi Ren
Journal:  Oncol Lett       Date:  2014-02-07       Impact factor: 2.967

  4 in total

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