| Literature DB >> 21351253 |
Cynthia C Sprenger1, Stephen R Plymate, May J Reed.
Abstract
Age is the greatest risk factor for the development of epithelial cancers. In this minireview, we will examine key extracellular matrix and matricellular components, their changes with aging, and discuss how these alterations might influence the subsequent progression of cancer in the aged host. Because of the tight correlation between advanced age and the prevalence of prostate cancer, we will use prostate cancer as the model throughout this minireview.Entities:
Mesh:
Year: 2010 PMID: 21351253 PMCID: PMC3024458 DOI: 10.1002/ijc.25615
Source DB: PubMed Journal: Int J Cancer ISSN: 0020-7136 Impact factor: 7.396