Preoperative management with nitrogen inhalation therapy for a low-birth weight infant with tetralogy of Fallot and absent pulmonary valve.

Tetralogy of Fallot and absent pulmonary valve (TOF/APV) is a rare congenital heart disease. Patients with TOF/APV with severe clinical symptoms require surgical intervention for cardiac abnormality in the neonatal period, but the preoperative conditioning for surgical treatment is extremely complicated. We experienced a low-birth-weight patient with TOF/APV who was successfully treated by radical surgery at 63 days of age after long-term intensive management using nitrogen inhalation therapy.