Literature DB >> 21349916

Community-acquired pneumonia as an emergency: time for an aggressive intervention to lower mortality.

S Ewig1, A Torres.   

Abstract

Community-acquired pneumonia (CAP) is one of the major contemporary acute life-threatening conditions. Short-term mortality reaches 14% (7% if nursing-home residents and bedridden patients are excluded) and long-term mortality reaches 50% within 5 yrs. CAP and acute myocardial infarction (AMI) have a lot in common with regard to acuity, prognosis, need for risk stratification and early intervention, and secondary prevention measures. The obvious success in the treatment of AMI is due to an effective organisation of pre-hospital care and evidence-based interventions in the hospital within defined timescales. Less evidence is available about effective strategies to lower short- and long-term mortality in patients with CAP. Nevertheless, it is estimated that ∼ 30% of hospitalised patients with CAP could be subject to a management approach in parallel to that of acute coronary syndrome (ACS). Management of patients with severe CAP should be intensified using all elements that have been established in the care for patients with ACS and stroke. One of the main challenges of future research will be to define whether and which additional patients at risk of mortality truly profit from timely and structured interventions. In the meantime, patients at increased risk of death according to clinical prediction tools should also be subject to an aggressive management approach.

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Year:  2011        PMID: 21349916     DOI: 10.1183/09031936.00199810

Source DB:  PubMed          Journal:  Eur Respir J        ISSN: 0903-1936            Impact factor:   16.671


  20 in total

1.  Why do nonsurvivors from community-acquired pneumonia not receive ventilatory support?

Authors:  Torsten T Bauer; Tobias Welte; Richard Strauss; Helge Bischoff; Klaus Richter; Santiago Ewig
Journal:  Lung       Date:  2013-05-05       Impact factor: 2.584

2.  A risk score for predicting hospitalization for community-acquired pneumonia in ITP using nationally representative data.

Authors:  Ye-Jun Wu; Ming Hou; Hui-Xin Liu; Jun Peng; Liang-Ming Ma; Lin-Hua Yang; Ru Feng; Hui Liu; Yi Liu; Jia Feng; Hong-Yu Zhang; Ze-Ping Zhou; Wen-Sheng Wang; Xu-Liang Shen; Peng Zhao; Hai-Xia Fu; Qiao-Zhu Zeng; Xing-Lin Wang; Qiu-Sha Huang; Yun He; Qian Jiang; Hao Jiang; Jin Lu; Xiang-Yu Zhao; Xiao-Su Zhao; Ying-Jun Chang; Lan-Ping Xu; Yue-Ying Li; Qian-Fei Wang; Xiao-Hui Zhang
Journal:  Blood Adv       Date:  2020-11-24

3.  The effect of marital status on the presentation and outcomes of elderly male veterans hospitalized for pneumonia.

Authors:  Mark L Metersky; Michael J Fine; Eric M Mortensen
Journal:  Chest       Date:  2012-10       Impact factor: 9.410

4.  Host Transcriptional Signatures Predict Etiology in Community-Acquired Pneumonia: Potential Antibiotic Stewardship Tools.

Authors:  William W Siljan; Dhanasekaran Sivakumaran; Christian Ritz; Synne Jenum; Tom Hm Ottenhoff; Elling Ulvestad; Jan C Holter; Lars Heggelund; Harleen Ms Grewal
Journal:  Biomark Insights       Date:  2022-06-06

Review 5.  Long-term prognosis in community-acquired pneumonia.

Authors:  Marcos I Restrepo; Paola Faverio; Antonio Anzueto
Journal:  Curr Opin Infect Dis       Date:  2013-04       Impact factor: 4.915

6.  Respiratory infection and the impact of pulmonary immunity on lung health and disease.

Authors:  Joseph P Mizgerd
Journal:  Am J Respir Crit Care Med       Date:  2012-07-12       Impact factor: 21.405

7.  Usefulness of midregional proadrenomedullin to predict poor outcome in patients with community acquired pneumonia.

Authors:  Susana Gordo-Remartínez; María Calderón-Moreno; Juan Fernández-Herranz; Ana Castuera-Gil; Mar Gallego-Alonso-Colmenares; Carolina Puertas-López; José A Nuevo-González; Domingo Sánchez-Sendín; Mercedes García-Gámiz; José A Sevillano-Fernández; Luis A Álvarez-Sala; Juan A Andueza-Lillo; José M de Miguel-Yanes
Journal:  PLoS One       Date:  2015-06-01       Impact factor: 3.240

8.  Interleukin-6 and procalcitonin as biomarkers in mortality prediction of hospitalized patients with community acquired pneumonia.

Authors:  Ilija Andrijevic; Jovan Matijasevic; Ljiljana Andrijevic; Tomi Kovacevic; Bojan Zaric
Journal:  Ann Thorac Med       Date:  2014-07       Impact factor: 2.219

9.  Clinical implications for patients treated inappropriately for community-acquired pneumonia in the emergency department.

Authors:  Scott T Micek; Adam Lang; Brian M Fuller; Nicholas B Hampton; Marin H Kollef
Journal:  BMC Infect Dis       Date:  2014-02-05       Impact factor: 3.090

10.  Phenotyping community-acquired pneumonia according to the presence of acute respiratory failure and severe sepsis.

Authors:  Stefano Aliberti; Anna Maria Brambilla; James D Chalmers; Catia Cilloniz; Julio Ramirez; Angelo Bignamini; Elena Prina; Eva Polverino; Paolo Tarsia; Alberto Pesci; Antoni Torres; Francesco Blasi; Roberto Cosentini
Journal:  Respir Res       Date:  2014-03-04
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