| Literature DB >> 21349364 |
Massimiliano Fabbiani1, Simona Di Giambenedetto, Michela Sali, Salvatore Farina, Paola Sansonetti, Enrica Tamburrini, Lorenzo Zileri Dal Verme, Giovanni Delogu, Andrea De Luca, David Kelvin, Roberto Cauda, Giovanni Fadda.
Abstract
Immunogenicity of influenza A (H1N1)v MF59-adjuvanted vaccine was studied in HIV-infected patients. The vaccine was effective in inducing a protective immune response in patients with a CD4 >200 cells/μL while individuals with CD4 <200 cells/μL showed lower rates of seroconversion and seroprotection. These results underscore the usefulness of immunization against influenza in HIV-infected patients, though a boosting dose of vaccine may be required in seriously immunocompromised patients.Entities:
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Year: 2011 PMID: 21349364 DOI: 10.1016/j.vaccine.2011.02.020
Source DB: PubMed Journal: Vaccine ISSN: 0264-410X Impact factor: 3.641