BACKGROUND: Mediastinitis due to Acinetobacter baumannii is rare. METHODS: We report a case of mediastinitis caused by pan-resistant A. baumannii in a patient with multiple comorbidities who underwent cardiopulmonary bypass and we also present a literature review. RESULTS: Successful treatment consisted of surgical debridement plus drainage, and tigecycline administration for three weeks. CONCLUSION: Surgical source control along with effective antibiotics is essential in the treatment of mediastinitis. Tigecycline has the potential to be an option for pan-resistant A. baumannii mediastinitis.
BACKGROUND:Mediastinitis due to Acinetobacter baumannii is rare. METHODS: We report a case of mediastinitis caused by pan-resistant A. baumannii in a patient with multiple comorbidities who underwent cardiopulmonary bypass and we also present a literature review. RESULTS: Successful treatment consisted of surgical debridement plus drainage, and tigecycline administration for three weeks. CONCLUSION: Surgical source control along with effective antibiotics is essential in the treatment of mediastinitis. Tigecycline has the potential to be an option for pan-resistant A. baumannii mediastinitis.
Authors: Justin R Lenhard; Nicholas M Smith; Zackery P Bulman; Xun Tao; Visanu Thamlikitkul; Beom S Shin; Roger L Nation; Jian Li; Jürgen B Bulitta; Brian T Tsuji Journal: Antimicrob Agents Chemother Date: 2017-02-23 Impact factor: 5.191