Literature DB >> 21347998

Cytotoxic triterpenoid saponins from the rhizomes of Anemone taipaiensis.

Xiao-Yang Wang1, Xiao-Li Chen, Hai-Feng Tang, Hui Gao, Xiang-Rong Tian, Ping-Hu Zhang.   

Abstract

Two new oleanane-type triterpenoid saponins, 1 and 2, and a new natural product, 3, together with five known saponins, 4- 8, were isolated from the rhizomes of ANEMONE TAIPAIENSIS. Their structures were elucidated by extensive spectroscopic analysis and chemical evidences. Six saponins, 1, 2, 4- 7, which possessed a free carboxylic group at C-28, exhibited significant cytotoxicity against human leukemia HL-60 cells and human hepatocellular carcinoma Hep-G2 cells with IC (50) values in the range of 1.31-10.12 µM. © Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2011        PMID： 21347998     DOI： 10.1055/s-0030-1270821

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  9 in total

1.  Triterpenoid saponins from the root of Anemone tomentosa.

Authors:  Yi Wang; Wei Kang; Liang-jian Hong; Wen-li Hai; Xiao-yang Wang; Hai-feng Tang; Xiang-rong Tian
Journal:  J Nat Med       Date:  2012-03-06       Impact factor: 2.343

2.  SB365 inhibits angiogenesis and induces apoptosis of hepatocellular carcinoma through modulation of PI3K/Akt/mTOR signaling pathway.

Authors:  Sang-Won Hong; Kyung Hee Jung; Hee-Seung Lee; Myung-Joo Choi; Mi Kwon Son; Hong-Mei Zheng; Soon-Sun Hong
Journal:  Cancer Sci       Date:  2012-09-25       Impact factor: 6.716

3.  Triterpenoid saponin flaccidoside II from Anemone flaccida triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors via the MAPK-HO-1 pathway.

Authors:  Lin-Tao Han; Yin Fang; Yan Cao; Feng-Hua Wu; E Liu; Guo-Yan Mo; Fang Huang
Journal:  Onco Targets Ther       Date:  2016-04-05       Impact factor: 4.147

4.  Paris saponin H inhibits the proliferation of glioma cells through the A1 and A3 adenosine receptor‑mediated pathway.

Authors:  Linlin Bi; Yang Liu; Qian Yang; Xuanxuan Zhou; Hua Li; Yang Liu; Jie Li; Yunyang Lu; Haifeng Tang
Journal:  Int J Mol Med       Date:  2021-02-04       Impact factor: 4.101

5.  Saponin 1 induces apoptosis and suppresses NF-κB-mediated survival signaling in glioblastoma multiforme (GBM).

Authors:  Juan Li; Haifeng Tang; Yun Zhang; Chi Tang; Bo Li; Yuangang Wang; Zhenhui Gao; Peng Luo; Anan Yin; Xiaoyang Wang; Guang Cheng; Zhou Fei
Journal:  PLoS One       Date:  2013-11-21       Impact factor: 3.240

6.  Antineoplastic agents. 595. Structural modifications of betulin and the X-ray crystal structure of an unusual betulin amine dimer.

Authors:  George R Pettit; Noeleen Melody; Frank Hempenstall; Jean-Charles Chapuis; Thomas L Groy; Lee Williams
Journal:  J Nat Prod       Date:  2014-04-02       Impact factor: 4.050

7.  Triterpenoid Saponins from Anemone rivularis var. Flore-Minore and Their Anti-Proliferative Activity on HSC-T6 Cells.

Authors:  Xiao-Yang Wang; Hui Gao; Xiao-Jie Xie; Jirimubatu Jurhiin; Mu-Zi-He Zhang; Yan-Ping Zhou; Rui Liu; Meng Ning; Jin Han; Hai-Feng Tang
Journal:  Molecules       Date:  2018-02-23       Impact factor: 4.411

8.  Reduction of SCUBE3 by a new marine-derived asterosaponin leads to arrest of glioma cells in G1/S.

Authors:  Peng-Cheng Qiu; Yun-Yang Lu; Shan Zhang; Hua Li; Han Bao; Yu-Qiang Ji; Fei Fang; Hai-Feng Tang; Guang Cheng
Journal:  Oncogenesis       Date:  2020-08-06       Impact factor: 7.485

9.  Promotion of Ros-mediated Bax/Cyt-c apoptosis by polyphyllin II leads to suppress growth and aggression of glioma cells.

Authors:  Guang Cheng; Yu-Ye Xue; Fei Fang; Guang-Qiang Sun; Yun-Yang Lu; Yu-Qiang Ji; Peng-Cheng Qiu; Hai-Feng Tang
Journal:  Transl Cancer Res       Date:  2021-09       Impact factor: 1.241
  9 in total

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