Literature DB >> 21346513

Optimum time to start antiretroviral therapy in patients with HIV-associated tuberculosis: before or after tuberculosis diagnosis?

Andrew D Kerkhoff1, Robin Wood, Stephen D Lawn.   

Abstract

WHO policy states that tuberculosis (TB) should be diagnosed and treated before starting antiretroviral treatment (ART). However, during the pre-ART screening period, diagnosing or excluding TB can be a lengthy process and may cause undesirable delays in ART initiation. In this observational study from South Africa, we report that initiation of ART before TB treatment in patients with delayed diagnoses of culture-positive prevalent TB was not associated with adverse clinical, immunological or virological outcomes during 12-month follow-up.

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Year:  2011        PMID： 21346513     DOI： 10.1097/QAD.0b013e328345ee32

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  4 in total

1.  Risk scores for predicting early antiretroviral therapy mortality in sub-Saharan Africa to inform who needs intensification of care: a derivation and external validation cohort study.

Authors:  Andrew F Auld; Katherine Fielding; Tefera Agizew; Alice Maida; Anikie Mathoma; Rosanna Boyd; Anand Date; Sherri L Pals; George Bicego; Yuliang Liu; Ray W Shiraishi; Peter Ehrenkranz; Christopher Serumola; Unami Mathebula; Heather Alexander; Salome Charalambous; Courtney Emerson; Goabaone Rankgoane-Pono; Pontsho Pono; Alyssa Finlay; James C Shepherd; Charles Holmes; Tedd V Ellerbrock; Alison D Grant
Journal:  BMC Med       Date:  2020-11-09       Impact factor: 8.775

Review 2.  Systematic review of TST responses in people living with HIV in under-resourced settings: implications for isoniazid preventive therapy.

Authors:  Andrew D Kerkhoff; Katharina Kranzer; Taraz Samandari; Jessica Nakiyingi-Miiro; Christopher C Whalen; Anthony D Harries; Stephen D Lawn
Journal:  PLoS One       Date:  2012-11-27       Impact factor: 3.240

3.  Six-month mortality among HIV-infected adults presenting for antiretroviral therapy with unexplained weight loss, chronic fever or chronic diarrhea in Malawi.

Authors:  Monique van Lettow; Ann Åkesson; Alexandra L C Martiniuk; Andrew Ramsay; Adrienne K Chan; Suzanne T Anderson; Anthony D Harries; Elizabeth Corbett; Robert S Heyderman; Rony Zachariah; Richard A Bedell
Journal:  PLoS One       Date:  2012-11-19       Impact factor: 3.240

4.  Outcomes and Diagnostic Processes in Outpatients with Presumptive Tuberculosis in Zomba District, Malawi.

Authors:  Monique van Lettow; Richard Bedell; Sonia Maosa; Kenneth Phiri; Adrienne K Chan; Edson Mwinjiwa; Aunex Kwekwesa; Harry Kawonga; Martias Joshua; Anthony D Harries; Joep J van Oosterhout
Journal:  PLoS One       Date:  2015-11-10       Impact factor: 3.240
  4 in total

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