Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Improvement of prostate cancer detection by integrating the PSA test with miRNA expression profiling.

Literature DB >> 21345070

Improvement of prostate cancer detection by integrating the PSA test with miRNA expression profiling.

Yubin Hao¹, Yuan Zhao, Xiaoyun Zhao, Chunnian He, Xiaowu Pang, T C Wu, Joseph A Califano, Xinbin Gu.

Abstract

Prostate-specific antigen (PSA) test is limited in prostate cancer diagnosis due to its inaccuracy. A new approach which integrates the PSA test with miRNA profiling was investigated to improve prostate cancer diagnosis. Six prostate cancer-related miRNAs (miR-16, -21, -34c, -101, -125b, -141) were tested in five cultured prostate cell lines and 20 human prostate specimens. We found that the miRNA expression profiles were significantly different between nontumorigenic and tumorigenic cell lines and specimens. Positive predictive value analysis of prostate cancer was increased from 40% to 87.5% by integrating patient PSA blood levels with miR-21 and miR-141 profiles.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：

Year: 2011 PMID： 21345070 PMCID： PMC3305797 DOI： 10.3109/07357907.2011.554477

Source DB: PubMed Journal: Cancer Invest ISSN： 0735-7907 Impact factor: 2.176

38 in total

1. Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b.

Authors: Gary K Scott; Andrei Goga; Dipa Bhaumik; Crystal E Berger; Christopher S Sullivan; Christopher C Benz
Journal: J Biol Chem Date: 2006-11-16 Impact factor: 5.157

2. Clinical characteristics and biopsy specimen features in African-American and white men without prostate cancer.

Authors: J A Eastham; R A May; T Whatley; A Crow; D D Venable; O Sartor
Journal: J Natl Cancer Inst Date: 1998-05-20 Impact factor: 13.506

3. miR-15 and miR-16 induce apoptosis by targeting BCL2.

Authors: Amelia Cimmino; George Adrian Calin; Muller Fabbri; Marilena V Iorio; Manuela Ferracin; Masayoshi Shimizu; Sylwia E Wojcik; Rami I Aqeilan; Simona Zupo; Mariella Dono; Laura Rassenti; Hansjuerg Alder; Stefano Volinia; Chang-Gong Liu; Thomas J Kipps; Massimo Negrini; Carlo M Croce
Journal: Proc Natl Acad Sci U S A Date: 2005-09-15 Impact factor: 11.205

4. Prostate-specific antigen (PSA) and PSA density: racial differences in men without prostate cancer.

Authors: R J Henderson; J A Eastham; D J Culkin; M W Kattan; T Whatley; J Mata; D Venable; O Sartor
Journal: J Natl Cancer Inst Date: 1997-01-15 Impact factor: 13.506

5. p53 abnormalities in primary prostate cancer: single-strand conformation polymorphism analysis of complementary DNA in comparison with genomic DNA. The Cooperative Prostate Network.

Authors: P H Gumerlock; S G Chi; X B Shi; H J Voeller; J W Jacobson; E P Gelmann; R W deVere White
Journal: J Natl Cancer Inst Date: 1997-01-01 Impact factor: 13.506

Review 6. Prostate carcinogenesis and inflammation: emerging insights.

Authors: Ganesh S Palapattu; Siobhan Sutcliffe; Patrick J Bastian; Elizabeth A Platz; Angelo M De Marzo; William B Isaacs; William G Nelson
Journal: Carcinogenesis Date: 2004-10-21 Impact factor: 4.944

7. Correlation between DNA repair capacity in lymphocytes and acute side effects to skin during radiotherapy in nasopharyngeal cancer patients.

Authors: Wei-dong Wang; Zheng-tang Chen; De-zhi Li; Zheng-huai Cao; Shi-liang Sun; Ping Pu; Xiao-pin Chen
Journal: Clin Cancer Res Date: 2005-07-15 Impact factor: 12.531

8. MicroRNA gene expression deregulation in human breast cancer.

Authors: Marilena V Iorio; Manuela Ferracin; Chang-Gong Liu; Angelo Veronese; Riccardo Spizzo; Silvia Sabbioni; Eros Magri; Massimo Pedriali; Muller Fabbri; Manuela Campiglio; Sylvie Ménard; Juan P Palazzo; Anne Rosenberg; Piero Musiani; Stefano Volinia; Italo Nenci; George A Calin; Patrizia Querzoli; Massimo Negrini; Carlo M Croce
Journal: Cancer Res Date: 2005-08-15 Impact factor: 12.701

9. [Correlation between EPS composition and elevated serum PSA in prostatitis patients].

Authors: Runguo Gu; Chunwen Zhou; Qingzheng Ma
Journal: Zhonghua Nan Ke Xue Date: 2004-06

10. Chronic inflammation in benign prostate hyperplasia is associated with focal upregulation of cyclooxygenase-2, Bcl-2, and cell proliferation in the glandular epithelium.

Authors: Wanzhong Wang; Anders Bergh; Jan-Erik Damber
Journal: Prostate Date: 2004-09-15 Impact factor: 4.104

20 in total

Review 1. Restoring TGFβ1 pathway-related microRNAs: possible impact in metastatic prostate cancer development.

Authors: Juliana Inês Santos; Ana Luísa Teixeira; Francisca Dias; Mónica Gomes; Augusto Nogueira; Joana Assis; Rui Medeiros
Journal: Tumour Biol Date: 2014-04-25

Review 2. MicroRNA-21 gene and cancer.

Authors: Yong Huang; You Bing Yang; Xiao Hui Zhang; Xue Li Yu; Zhan Bin Wang; Xiang Chao Cheng
Journal: Med Oncol Date: 2013-01-01 Impact factor: 3.064

3. MicroRNA-21 regulates biological behavior by inducing EMT in human cholangiocarcinoma.

Authors: Zhen Liu; Zhi-Yuan Jin; Chen-Hai Liu; Fang Xie; Xian-Sheng Lin; Qiang Huang
Journal: Int J Clin Exp Pathol Date: 2015-05-01

4. DNA-Based Smart Reagent for Detecting Alzheimer's Associated MicroRNAs.

Authors: Arun Richard Chandrasekaran; Ken Halvorsen
Journal: ACS Sens Date: 2021-09-07 Impact factor: 9.618

5. Concurrent HDAC and mTORC1 inhibition attenuate androgen receptor and hypoxia signaling associated with alterations in microRNA expression.

Authors: Leigh Ellis; Kristin Lehet; Swathi Ramakrishnan; Remi Adelaiye; Kiersten M Miles; Dan Wang; Song Liu; Peter Atadja; Michael A Carducci; Roberto Pili
Journal: PLoS One Date: 2011-11-07 Impact factor: 3.240