Literature DB >> 2134503

A mixed model of carcinogenesis with applications to retinoblastoma.

W Y Tan1, K P Singh.   

Abstract

This paper presents a mixed model of carcinogenesis and derives the incidence functions and the first four cumulants of the number of tumors. The model is then fitted to some retinoblastoma data from the SEER (Surveillance Epidemiology End Results) project of the National Cancer Institute for the years 1973-1982. In all the cases presented, the estimated incidence functions appear to fit the observed incidence curves quite well, suggesting the usefulness of the model.

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Year:  1990        PMID: 2134503     DOI: 10.1016/0025-5564(90)90125-i

Source DB:  PubMed          Journal:  Math Biosci        ISSN: 0025-5564            Impact factor:   2.144


  2 in total

1.  Analysis of retinoblastoma age incidence data using a fully stochastic cancer model.

Authors:  Mark P Little; Ruth A Kleinerman; Charles A Stiller; Guangquan Li; Mary E Kroll; Michael F G Murphy
Journal:  Int J Cancer       Date:  2011-06-10       Impact factor: 7.396

2.  Heterogeneity in multistage carcinogenesis and mixture modeling.

Authors:  Sandro Gsteiger; Stephan Morgenthaler
Journal:  Theor Biol Med Model       Date:  2008-07-21       Impact factor: 2.432

  2 in total

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