Literature DB >> 21344957

Endolymphatic hydrops in Meniere's disease detected by MRI after intratympanic administration of gadolinium: comparison with sudden deafness.

Arata Horii1, Yasuhiro Osaki, Tadashi Kitahara, Takao Imai, Atsuhiko Uno, Suetaka Nishiike, Norihiko Fujita, Hidenori Inohara.   

Abstract

CONCLUSION: The detection rate of endolymphatic hydrops was significantly higher in patients with Meniere's disease compared with those with sudden deafness, indicating that 3 T magnetic resonance imaging (MRI) with intratympanic gadolinium injection was effective in diagnosing endolymphatic hydrops.
OBJECTIVES: To compare the detection rate of endolymphatic hydrops between patients with Meniere's disease and sudden deafness as controls by 3 T MRI after intratympanic gadolinium injection with conventional pulse sequence such as two-dimensional fluid-attenuated inversion recovery.
METHODS: Ten patients with unilateral Meniere's disease and eight with sudden deafness underwent inner ear MRI 24 h after intratympanic gadolinium injection.
RESULTS: The endolymphatic space was detected as a low signal intensity area, while the perilymphatic space showed high intensity by gadolinium enhancement. Due to faint enhancement, images could not be evaluated in 1 of 10 patients with Meniere's disease. However, the other nine patients together with two of the eight with sudden deafness were diagnosed as having hydrops. The difference in detection rates between the two diseases was statistically significant. Two hydrops-positive cases with sudden deafness were considered to be of the secondary type of hydrops, because images were taken after partial recovery from hearing loss several months after the onset of the disease.

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Year:  2011        PMID: 21344957     DOI: 10.3109/00016489.2010.548403

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN: 0001-6489            Impact factor:   1.494


  6 in total

Review 1.  Visualization of endolymphatic hydrops with MR imaging in patients with Ménière's disease and related pathologies: current status of its methods and clinical significance.

Authors:  Shinji Naganawa; Tsutomu Nakashima
Journal:  Jpn J Radiol       Date:  2014-02-06       Impact factor: 2.374

2.  Value of Endolymphatic Hydrops and Perilymph Signal Intensity in Suspected Ménière Disease.

Authors:  J M van Steekelenburg; A van Weijnen; L M H de Pont; O D Vijlbrief; C C Bommeljé; J P Koopman; B M Verbist; H M Blom; S Hammer
Journal:  AJNR Am J Neuroradiol       Date:  2020-02-06       Impact factor: 3.825

3.  Effect of standard-dose Betahistine on endolymphatic hydrops: an MRI pilot study.

Authors:  R Gürkov; W Flatz; D Keeser; M Strupp; B Ertl-Wagner; E Krause
Journal:  Eur Arch Otorhinolaryngol       Date:  2012-07-04       Impact factor: 2.503

4.  Comparison of contrast effect on the cochlear perilymph after intratympanic and intravenous gadolinium injection.

Authors:  M Yamazaki; S Naganawa; M Tagaya; H Kawai; M Ikeda; M Sone; M Teranishi; H Suzuki; T Nakashima
Journal:  AJNR Am J Neuroradiol       Date:  2011-12-15       Impact factor: 3.825

Review 5.  What is Menière's disease? A contemporary re-evaluation of endolymphatic hydrops.

Authors:  R Gürkov; I Pyykö; J Zou; E Kentala
Journal:  J Neurol       Date:  2016-04-15       Impact factor: 4.849

Review 6.  Pathological significance and classification of endolymphatic hydrops in otological disorders.

Authors:  Michihiko Sone; Tadao Yoshida; Satofumi Sugimoto; Masumi Kobayashi; Masaaki Teranishi; Shinji Naganawa
Journal:  Nagoya J Med Sci       Date:  2022-08       Impact factor: 0.794

  6 in total

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